Manifold learning based data-driven modeling for soft biological tissues
Data-driven modeling directly utilizes experimental data with machine learning techniques
to predict a material's response without the necessity of using phenomenological constitutive …
to predict a material's response without the necessity of using phenomenological constitutive …
A physics-guided neural operator learning approach to model biological tissues from digital image correlation measurements
We present a data-driven workflow to biological tissue modeling, which aims to predict the
displacement field based on digital image correlation (DIC) measurements under unseen …
displacement field based on digital image correlation (DIC) measurements under unseen …
Changes in iris stiffness and permeability in primary angle closure glaucoma
Purpose: To evaluate the biomechanical properties of the iris by evaluating iris movement
during pupil constriction and to compare such properties between healthy and primary angle …
during pupil constriction and to compare such properties between healthy and primary angle …
Quantification of iris elasticity using acoustic radiation force optical coherence elastography
Y Zhu, Y Zhang, G Shi, Q Xue, X Han, S Ai, J Shi… - Applied Optics, 2020 - opg.optica.org
Careful quantification of the changes in biomechanical properties of the iris can offer insight
into the pathophysiology of some ocular diseases. However, to date there has not been …
into the pathophysiology of some ocular diseases. However, to date there has not been …
[HTML][HTML] Increased iris stiffness in patients with a history of angle-closure glaucoma: an image-based inverse modeling analysis
AD Pant, P Gogte, V Pathak-Ray… - … & visual science, 2018 - jov.arvojournals.org
Purpose: Previous studies have shown that iris mechanical properties may play a role in the
pathophysiology of primary angle-closure glaucoma (PACG). Such studies, however, were …
pathophysiology of primary angle-closure glaucoma (PACG). Such studies, however, were …
[HTML][HTML] A computational multi-scale approach to investigate mechanically-induced changes in tricuspid valve anterior leaflet microstructure
The tricuspid valve is an atrioventricular valve that prevents blood backflow from the right
ventricle into the right atrium during ventricular contractions. It is important to study …
ventricle into the right atrium during ventricular contractions. It is important to study …
Heterogeneous Peridynamic Neural Operators: Discover Biotissue Constitutive Law and Microstructure From Digital Image Correlation Measurements
Human tissues are highly organized structures with specific collagen fiber arrangements
varying from point to point. The effects of such heterogeneity play an important role for tissue …
varying from point to point. The effects of such heterogeneity play an important role for tissue …
In vivo biomechanical assessment of iridial deformations and muscle contractions in human eyes
BN Safa, MR Bahrani Fard… - Journal of the Royal …, 2022 - royalsocietypublishing.org
The iris is a muscular organ whose deformations can cause primary angle-closure
glaucoma (PACG), a leading cause of blindness. PACG risk assessment does not consider …
glaucoma (PACG), a leading cause of blindness. PACG risk assessment does not consider …
[HTML][HTML] Iris Morphological and Biomechanical Factors Influencing Angle Closure During Pupil Dilation
Purpose: To use finite element (FE) analysis to assess what morphologic and biomechanical
factors of the iris and anterior chamber are more likely to influence angle narrowing during …
factors of the iris and anterior chamber are more likely to influence angle narrowing during …
Iris stromal cell nuclei deform to more elongated shapes during pharmacologically-induced miosis and mydriasis
Nuclear shape alteration in ocular tissues, which can be used as a metric for overall cell
deformation, may also lead to changes in gene expression and protein synthesis that could …
deformation, may also lead to changes in gene expression and protein synthesis that could …