Transient receptor potential vanilloid 1 (TRPV1) is an ion channel expressed on sensory
neurons triggering an influx of cations. TRPV1 receptors function as homotetramers …

Seeds contain a variety of phytochemicals that exhibit a wide range of biological activities.
Plant-derived compounds are often investigated for their antioxidant, anti-inflammatory …

Abstract α‐Spinasterol is a phytosterol found in various edible and non‐edible plant
sources. The edible plant materials containing α‐spinasterol include spinach leaves …

TRPV1 has been originally cloned as the heat and capsaicin receptor implicated in acute
pain signalling, while further research has shifted the focus to its importance in chronic pain …

Overcoming refractory epilepsy's resistance to the combination of antiepileptic drugs (AED),
mitigating side effects, and preventing sudden unexpected death in epilepsy are critical …

A significant proportion of neonatal and childhood seizures are poorly controlled by existing
anti-seizure drugs (ASDs), likely due to prominent differences in ionic homeostasis and …

Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …

Ethnopharmacological relevance: The genus Alternanthera (Amaranthaceae) comprises
139 species including 14 species used traditionally for the treatment of various ailments …

Central nervous system (CNS) disorders like Alzheimer's disease (AD), Parkinson disease
(PD), stroke, epilepsy, depression, and bipolar disorder have a high impact on both medical …

The use of Cannabis for medicinal purposes has been documented since ancient times,
where one of its principal cannabinoids extracted from Cannabis sativa, cannabidiol (CBD) …