Computational chemistry in structure-based solute carrier transporter drug design: Recent advances and future perspectives
G Tu, T Fu, G Zheng, B Xu, R Gou, D Luo… - Journal of chemical …, 2024 - ACS Publications
Solute carrier transporters (SLCs) are a class of important transmembrane proteins that are
involved in the transportation of diverse solute ions and small molecules into cells. There are …
involved in the transportation of diverse solute ions and small molecules into cells. There are …
[HTML][HTML] Functional Characterization of Splice Variants in the Diagnosis of Albinism
M Diallo, C Courdier, E Mercier, A Sequeira… - International Journal of …, 2024 - mdpi.com
Albinism is a genetically heterogeneous disease in which 21 genes are known so far. Its
inheritance mode is autosomal recessive except for one X-linked form. The molecular …
inheritance mode is autosomal recessive except for one X-linked form. The molecular …
Two‐pore channel 2 is required for soluble adenylyl cyclase‐dependent regulation of melanosomal pH and melanin synthesis
D Zhou, Z Eraslan, D Miller, I Taylor… - Pigment Cell & …, 2024 - Wiley Online Library
Melanosomal pH is important for the synthesis of melanin as the rate‐limiting enzyme,
tyrosinase, is very pH‐sensitive. The soluble adenylyl cyclase (sAC) signaling pathway was …
tyrosinase, is very pH‐sensitive. The soluble adenylyl cyclase (sAC) signaling pathway was …