Heterocycles and their derivatives have been inspiring medicinal chemists to device novel,
greener and efficient ways to synthesized them as the majority of drugs available in the …

Background and purpose Non-small cell lung cancer (NSCLC) is a major pathological type
of lung cancer and accounts for more than 80% of all cases. In healthcare management, it is …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

The COVID-19 outbreak and the pandemic situation have hastened the research community
to design a novel drug and vaccine against its causative organism, the SARS-CoV-2. The …

Being attracted with their cardiotonic, antidiabetic, cough relieving activity, treatment of fever,
absorbent, anti-asthmatic, etc. activities reported in ancient Ayurvedic literature …

Parkinson's disease is characterized by a multifactorial nature that is linked to different
pathways. Among them, the abnormal deposition and accumulation of α-synuclein fibrils is …

Antifolates such as methotrexate (MTX) have been largely known as anticancer agents
because of their role in blocking nucleic acid synthesis and cell proliferation. Their …

Abstract Context SARS-CoV-2, responsible for COVID-19, has led to over 500 million
infections and more than 6 million deaths globally. There have been limited effective …

Abstract Coronavirus disease 2019 (COVID-19) persists and shook the global population
where the endgame to this pandemic is brought on by developing vaccines in record …

Molecular dynamics simulations have been developed as the most powerful tool in the field
of computational chemistry for the discovery of novel anti‐protozoal agents against malaria …