Carboranes in drug discovery, chemical biology and molecular imaging
A Marfavi, P Kavianpour, LM Rendina - Nature Reviews Chemistry, 2022 - nature.com
There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …
Boron agents for neutron capture therapy
K Hu, Z Yang, L Zhang, L Xie, L Wang, H Xu… - Coordination Chemistry …, 2020 - Elsevier
Boron neutron capture therapy (BNCT) is a potential cancer radiotherapeutic modality,
which takes advantage of the neutron capture response that occurs when boron (10 B) is …
which takes advantage of the neutron capture response that occurs when boron (10 B) is …
Carbaboranes as pharmacophores: properties, synthesis, and application strategies
M Scholz, E Hey-Hawkins - Chemical Reviews, 2011 - ACS Publications
Medicinal chemistry is still clearly dominated by organic chemistry. Most of the marketed
drugs are purely organic molecules. The right-hand neighbors of carbon in the periodic …
drugs are purely organic molecules. The right-hand neighbors of carbon in the periodic …
Boron science
NS Hosmane - New technologies and applications, 2011 - api.taylorfrancis.com
What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …
Polyhedral boranes for medical applications: Current status and perspectives
IB Sivaev, VV Bregadze - European Journal of Inorganic …, 2009 - Wiley Online Library
This review focuses on the current status and perspectives of the application of polyhedral
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …
Metal-catalyzed cross-coupling chemistry with polyhedral boranes
RM Dziedzic, AM Spokoyny - Chemical communications, 2019 - pubs.rsc.org
Over the past several decades, metal-catalyzed cross-coupling has emerged as a very
powerful strategy to functionalize carbon-based molecules. More recently, some of the cross …
powerful strategy to functionalize carbon-based molecules. More recently, some of the cross …
[HTML][HTML] Multi-functional boron-delivery agents for boron neutron capture therapy of cancers
Simple Summary Many boron-containing compounds have been synthesized and proposed
as boron-delivery agents for boron neutron capture therapy for cancers, including brain …
as boron-delivery agents for boron neutron capture therapy for cancers, including brain …
Radionuclide carriers for targeting of cancer
S Sofou - International journal of nanomedicine, 2008 - Taylor & Francis
This review describes strategies for the delivery of therapeutic radionuclides to tumor sites.
Therapeutic approaches are summarized in terms of tumor location in the body, and tumor …
Therapeutic approaches are summarized in terms of tumor location in the body, and tumor …
Polyhedral boron compounds as potential diagnostic and therapeutic antitumor agents
VI Bregadze, IB Sivaev… - Anti-Cancer Agents in …, 2006 - ingentaconnect.com
The use of polyhedral boron hydrides for cancer treatment is traditionally connected with
boron neutron capture therapy. More recently, polyhedral borate anions were proposed as …
boron neutron capture therapy. More recently, polyhedral borate anions were proposed as …
Applications of X-ray scattering in pharmaceutical science
The use of X-ray scattering techniques in pharmaceutical science is increasing, in part
through increased collaborations with the materials science community, and through …
through increased collaborations with the materials science community, and through …