It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

The quantification of noncovalent interactions is of paramount importance for the
understanding of binding mechanisms, including biological systems, for the design of drugs …

Molecular recognition in water involves contributions due to polar functional group
interactions, partial desolvation of polar and non-polar surfaces and changes in …

A series of N-arylimide molecular balances were developed to study and measure carbonyl–
aromatic (CO− π) interactions. Carbonyl oxygens were observed to form repulsive …

The description of substituents as electron donating or withdrawing leads to a perceived
dominance of through‐bond influences. The situation is compounded by the challenge of …

As a synthetic model for intra‐protein interactions that reinforce binding affinities between
proteins and ligands, the energetic interplay of binding and folding was investigated using …

The ability to control molecular-scale motion using electrostatic interactions was
demonstrated using an N-phenylsuccinimide molecular rotor with an electrostatic pyridyl …

Herein, various molecular balances used for comparing the strengths of intramolecular
noncovalent interactions are reviewed. Our overview indicates that considerable quantitative …

Fluorination of carbohydrate ligands of lectins is a useful approach to examine their binding
profile, improve their metabolic stability and lipophilicity, and convert them into 19 F NMR …

To investigate the nature and strength of noncovalent interactions at the fullerene surface,
molecular torsion balances consisting of C60 and organic moieties connected through a …