Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via
a balance between bone formation by osteoblasts and resorption by osteoclasts. These …

In 1892, JL Wolff proposed that bone could respond to mechanical and biophysical stimuli
as a dynamic organ. This theory presents a unique opportunity for investigations on bone …

It is a big challenge to design a biomimetic physical microenvironment with greater similarity
to in vivo tissue to observe real cell behaviors. We established a novel cell culture platform …

Bone is an active organ that continuously undergoes an orchestrated process of remodeling
throughout life. Bone tissue is uniquely capable of adapting to loading, hormonal, and other …

Recent advances in society have resulted in the emergence of both hyperlipidemia and
obesity as life-threatening conditions in people with implications for various types of …

Alveolar bone remodeling in orthodontic tooth movement (OTM) is a highly regulated
process that coordinates bone resorption by osteoclasts and new bone formation by …

Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of
the most common sites of metastasis for many solid tumors. Once cancer cells colonize in …

Osteoporosis (OP) is the most prevalent metabolic bone disease, characterized by the low
bone mass and microarchitectural deterioration of bone tissue. Glucocorticoid (GC) clinically …

Abstract Purpose of Review The goal of this review is to provide an overview of the impact
and underlying mechanism of oxidative stress on connexin channel function, and their roles …

Radiotherapy is an effective treatment for breast cancer and other thoracic tumors. However,
while high-energy radiotherapy treatment successfully kills cancer cells, radiation exposure …