Stem cell paracrine actions and tissue regeneration
PR Baraniak, TC McDevitt - Regenerative medicine, 2010 - Taylor & Francis
Stem cells have emerged as a key element of regenerative medicine therapies due to their
inherent ability to differentiate into a variety of cell phenotypes, thereby providing numerous …
inherent ability to differentiate into a variety of cell phenotypes, thereby providing numerous …
Stem cell‐based cell therapy in neurological diseases: a review
SU Kim, J De Vellis - Journal of neuroscience research, 2009 - Wiley Online Library
Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …
Cell-based drug delivery
Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
Stem and progenitor cell-mediated tumor selective gene therapy
KS Aboody, J Najbauer, MK Danks - Gene therapy, 2008 - nature.com
The poor prognosis for patients with aggressive or metastatic tumors and the toxic side
effects of currently available treatments necessitate the development of more effective tumor …
effects of currently available treatments necessitate the development of more effective tumor …
Heparan sulfate proteoglycan‐mediated dynamin‐dependent transport of neural stem cell exosomes in an in vitro blood–brain barrier model
Drug delivery to the brain is greatly hampered by the presence of the blood–brain barrier
(BBB) which tightly regulates the passage of molecules from blood to brain and vice versa …
(BBB) which tightly regulates the passage of molecules from blood to brain and vice versa …
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare
MF Corsten, K Shah - The lancet oncology, 2008 - thelancet.com
As our understanding of stem-cell behaviour rapidly increases, more and more reports
suggest that use of stem-cell therapy will extend well beyond regenerative medicine in the …
suggest that use of stem-cell therapy will extend well beyond regenerative medicine in the …
Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-β and suppress the growth of MCF-7 human breast cancer cells
H Ryu, JE Oh, KJ Rhee, SK Baik, J Kim, SJ Kang… - Cancer letters, 2014 - Elsevier
Although it has been reported that mesenchymal stem cells (MSCs) suppress tumor growth
in vitro and in vivo, little is known about the underlying molecular mechanisms. We found …
in vitro and in vivo, little is known about the underlying molecular mechanisms. We found …
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo
Adenoviral oncolytic virotherapy represents an attractive treatment modality for central
nervous system (CNS) neoplasms. However, successful application of virotherapy in clinical …
nervous system (CNS) neoplasms. However, successful application of virotherapy in clinical …
Neural stem cell-based therapies and glioblastoma management: Current evidence and clinical challenges
Gliomas, which account for nearly a quarter of all primary CNS tumors, present significant
contemporary therapeutic challenges, particularly the highest-grade variant (glioblastoma …
contemporary therapeutic challenges, particularly the highest-grade variant (glioblastoma …
Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1-and HGF-dependent manner
H Takeuchi, A Natsume, T Wakabayashi, C Aoshima… - Neuroscience …, 2007 - Elsevier
Neural stem cell (NSC) transplantation has exhibited considerable therapeutic potential in
spinal cord injury. However, most experiments in animals have been performed by injecting …
spinal cord injury. However, most experiments in animals have been performed by injecting …