Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Molecular imaging and disease theranostics with renal-clearable optical agents

P Cheng, K Pu - Nature Reviews Materials, 2021 - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

Activatable molecular probes for fluorescence-guided surgery, endoscopy and tissue biopsy

Y Zhang, G Zhang, Z Zeng, K Pu - Chemical Society Reviews, 2022 - pubs.rsc.org
The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Near‐infrared‐II molecular dyes for cancer imaging and surgery

S Zhu, R Tian, AL Antaris, X Chen, H Dai - Advanced Materials, 2019 - Wiley Online Library
Fluorescence bioimaging affords a vital tool for both researchers and surgeons to
molecularly target a variety of biological tissues and processes. This review focuses on …

ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

NIR‐II AIEgens: a win–win integration towards bioapplications

W Xu, D Wang, BZ Tang - Angewandte Chemie International …, 2021 - Wiley Online Library
Fluorescence imaging in the second near‐infrared (NIR‐II) window facilitated by
aggregation‐induced emission luminogens (AIEgens) is an emerging research field. NIR‐II …

Dual-locked spectroscopic probes for sensing and therapy

L Wu, J Huang, K Pu, TD James - Nature Reviews Chemistry, 2021 - nature.com
Optical imaging probes allow us to detect and uncover the physiological and pathological
functions of an analyte of interest at the molecular level in a non-invasive, longitudinal …

NIR-II bioimaging of small organic molecule

Y Su, B Yu, S Wang, H Cong, Y Shen - Biomaterials, 2021 - Elsevier
In recent years, people have been actively exploring new imaging methods with high
biological imaging performance because the clinical image definition and depth in vivo …