G-quadruplexes: a promising target for cancer therapy
DNA and RNA can fold into a variety of alternative conformations. In recent years, a
particular nucleic acid structure was discussed to play a role in malignant transformation and …
particular nucleic acid structure was discussed to play a role in malignant transformation and …
Copper (II) complexes with naringenin and hesperetin: cytotoxic activity against A 549 human lung adenocarcinoma cells and investigation on the mode of action
LV Tamayo, LR Gouvea, AC Sousa, RM Albuquerque… - Biometals, 2016 - Springer
Abstract Copper (II) complexes [Cu (H 2 O) 2 (L1)(phen)](ClO 4)(1) and [Cu (H 2
O)(L2)(phen)](ClO 4)(2)(HL1= naringenin; HL2= hesperetin) were obtained, in which an …
O)(L2)(phen)](ClO 4)(2)(HL1= naringenin; HL2= hesperetin) were obtained, in which an …
Copper (II) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups …
To investigate the effect of different halogen substituents and leaving groups and the
flexibility of ligands on the anticancer activity of copper complexes, sixteen copper (II) …
flexibility of ligands on the anticancer activity of copper complexes, sixteen copper (II) …
Synthesis and characterization of novel Cu (II), Pd (II) and Pt (II) complexes with 8-Ethyl-2-hydroxytricyclo (7.3. 1.02, 7) tridecan-13-one-thiosemicarbazone …
New Cu (II), Pd (II) and Pt (II) complexes,(Cu (L)(H2O) 2 (OAc))(1),(Cu (HL)(H2O) 2
(SO4))(2),(Cu (L)(H2O) 2 (NO3))(3),(Cu (L)(H2O) 2 (ClO4))(4),(Cu (L) 2 (H2O) 2)(5),(Pd …
(SO4))(2),(Cu (L)(H2O) 2 (NO3))(3),(Cu (L)(H2O) 2 (ClO4))(4),(Cu (L) 2 (H2O) 2)(5),(Pd …
Synthesis, crystal structure and biological evaluation of a new dasatinib copper (II) complex as telomerase inhibitor
QP Qin, T Meng, MX Tan, YC Liu, XJ Luo… - European Journal of …, 2018 - Elsevier
A new copper (II) complex of dasatinib (DAS) was synthesized and characterized via ESI-
MS, UV–Vis, IR, single-crystal X-ray diffraction analysis, 1 H and 13 C NMR spectroscopy …
MS, UV–Vis, IR, single-crystal X-ray diffraction analysis, 1 H and 13 C NMR spectroscopy …
Structure and magnetic behavior of unpredictable EE-azide bridged tetranuclear Mn (II) complex with ONO-donor hydrazone ligand and its transformation to dinuclear …
The reaction of manganese (II) chloride tetrahydrate with sodium azide and ONO-donor
hydrazone ligand,(H 2 L=(E)-3-hydroxy-N′-((Z)-4-hydroxy-4-phenylbut-3-en-2-ylidene)-2 …
hydrazone ligand,(H 2 L=(E)-3-hydroxy-N′-((Z)-4-hydroxy-4-phenylbut-3-en-2-ylidene)-2 …
Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease
D Palanimuthu, Z Wu, PJ Jansson, N Braidy… - Dalton …, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is characterized by multiple pathological hallmarks, including β-
amyloid aggregation, oxidative stress, and metal dys-homeostasis. In the absence of …
amyloid aggregation, oxidative stress, and metal dys-homeostasis. In the absence of …
Synthesis, spectral characterization, DNA/BSA binding, antimicrobial and in vitro cytotoxicity of cobalt (III) complexes containing 7-hydroxy-4-oxo-4H-chromene Schiff …
G Kalaiarasi, S Dharani, SRJ Rajkumar, M Ranjani… - Inorganica Chimica …, 2021 - Elsevier
The present work deals with the synthesis and characterization of four Co (III) complexes
derived from 7-hydroxy-4-oxo-4H-chromene-3-carbaldehyde-4 (N)-substituted …
derived from 7-hydroxy-4-oxo-4H-chromene-3-carbaldehyde-4 (N)-substituted …
G-quadruplex vs. duplex-DNA binding of nickel (II) and zinc (II) Schiff base complexes
Abstract Novel nickel (II)(1) and zinc (II)(2) complexes of a Salen-like ligand, carrying a
pyrimidine ring on the N, N′ bridge, were synthesized and characterized. Their interaction …
pyrimidine ring on the N, N′ bridge, were synthesized and characterized. Their interaction …
The interaction of Schiff Base complexes of nickel (II) and zinc (II) with duplex and G-quadruplex DNA
The duplex and G-quadruplex DNA-binding of six nickel (II) and zinc (II) complexes of three
salphen-like ligands (salphen= N, N′-bis-salicylidene-1, 2-phenylenediaminato) was …
salphen-like ligands (salphen= N, N′-bis-salicylidene-1, 2-phenylenediaminato) was …