[HTML][HTML] GSTP1 and cancer: Expression, methylation, polymorphisms and signaling

J Cui, G Li, J Yin, L Li, Y Tan… - International …, 2020 - spandidos-publications.com
Abstract Glutathione S‑transferase Pi (GSTP1) is an isozyme encoded by the GST pi gene
that plays an important regulatory role in detoxification, anti‑oxidative damage, and the …

[HTML][HTML] Glutathione transferase P1-1 an enzyme useful in biomedicine and as biomarker in clinical practice and in environmental pollution

A Bocedi, A Noce, G Marrone, G Noce, G Cattani… - Nutrients, 2019 - mdpi.com
Glutathione transferase P1-1 (GSTP1-1) is expressed in some human tissues and is
abundant in mammalian erythrocytes (here termed e-GST). This enzyme is able to detoxify …

[HTML][HTML] Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations

A Sharma, A Pandey, S Sharma, I Chatterjee… - Meta gene, 2014 - Elsevier
Glutathione S-transferases (GSTs) belong to a super family of phase II detoxification
enzymes, which play an important role in protecting cells from damage caused by …

Significance of polymorphisms and expression of enzyme‐encoding genes related to glutathione in hematopoietic cancers and solid tumors

S Zmorzyński, G Świderska-Kołacz… - BioMed Research …, 2015 - Wiley Online Library
Antioxidant compounds such as glutathione and its enzymes have become the focus of
attention of medical sciences. Glutathione, a specific tripeptide, is involved in many …

Glutathione S-transferase Gene Polymorphisms and Susceptibility to Acute Myeloid Leukemia: Meta-analyses

HR He, HS You, JY Sun, SS Hu, Y Ma… - Japanese Journal of …, 2014 - academic.oup.com
Objective A large body of evidence has shown the possible relevance of polymorphisms of
the genes that encode glutathione S-transferase μ, π and θ (GSTM1, GSTP1 and GST1 …

From six gene polymorphisms of the antioxidant system, only GPX Pro198Leu and GSTP1 Ile105Val modulate the risk of acute myeloid leukemia

C Bănescu, M Iancu, AP Trifa, M Cândea… - Oxidative Medicine …, 2016 - Wiley Online Library
Oxidative stress might contribute to the occurrence of cancers, including the hematological
ones. Various genetic polymorphisms were shown to increase the quantity of reactive …

[HTML][HTML] Genetic polymorphism of GSTP1, GSTM1 and GSTT1 genes and susceptibility to chronic myeloid leukaemia

HME Idris, AY Elderdery, HB Khalil… - Asian Pacific Journal of …, 2020 - ncbi.nlm.nih.gov
Background: The development of cancer results from an imbalance between exposure to
carcinogens and the capacity of various enzyme systems engaged in activation or in the …

Glutathione S-transferase gene polymorphisms and susceptibility to chronic myeloid leukemia

H He, X Zhang, J Sun, S Hu, Y Ma, Y Dong, J Lu - Tumor Biology, 2014 - Springer
Abstract Glutathione S-transferase (GST), a phase II metabolizing enzyme, plays an
important role in the cellar defense system, and its activity may modulate leukemia risk. A …

Association of DNA repair and xenobiotic pathway gene polymorphisms with genetic susceptibility to gastric cancer patients in West Bengal, India

S Ghosh, S Ghosh, B Bankura, ML Saha, S Maji… - Tumor Biology, 2016 - Springer
Gastric cancer is one of the most common malignancies in India. DNA repair gene or
xenobiotic pathway gene polymorphisms have recently been shown to affect individual …

Glutathione-S-transferase polymorphisms (GSTM1, GSTT1 and GSTP1) and acute leukemia risk in Asians: a meta-analysis

ZH Tang, C Zhang, P Cheng, HM Sun… - Asian Pacific journal …, 2014 - koreascience.kr
The association between glutathione-S-transferase polymorphisms (GSTM1, GSTT1 and
GSTP1) and risk of acute leukemia in Asians remains controversial. This study was therefore …