The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …

D Haspula, MA Clark - International journal of molecular sciences, 2020 - mdpi.com
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

[HTML][HTML] Role of cannabis in cardiovascular disorders

H Goyal, HH Awad, JK Ghali - Journal of thoracic disease, 2017 - ncbi.nlm.nih.gov
The growing popularity of medical and recreational consumption of cannabis, especially
among the youth, raises immediate concerns regarding its safety and long-terms effects. The …

Enhanced endocannabinoid tone as a potential target of pharmacotherapy

M Toczek, B Malinowska - Life sciences, 2018 - Elsevier
The endocannabinoid system is up-regulated in numerous pathophysiological states such
as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular …

Marijuana: current concepts

DE Greydanus, EK Hawver, MM Greydanus… - Frontiers in public …, 2013 - frontiersin.org
Marijuana (cannabis) remains a controversial drug in the twenty-first century. This paper
considers current research on use of Cannabis sativa and its constituents such as the …

Medical consequences of marijuana use: a review of current literature

AJ Gordon, JW Conley, JM Gordon - Current psychiatry reports, 2013 - Springer
With the advent of legalization of marijuana for medicinal and recreational purposes, and the
increase use of marijuana, healthcare providers will be increasingly confronted with …

Vascular targets for cannabinoids: animal and human studies

C Stanley, SE O'Sullivan - British journal of pharmacology, 2014 - Wiley Online Library
Application of cannabinoids and endocannabinoids to perfused vascular beds or individual
isolated arteries results in changes in vascular resistance. In most cases, the result is …

[HTML][HTML] CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial

M Kumric, G Dujic, J Vrdoljak, K Svagusa… - Biomedicine & …, 2023 - Elsevier
Data concerning the effects of cannabidiol (CBD) on blood pressure (BP) is controversial.
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …

[HTML][HTML] Legalized cannabis in Colorado emergency departments: a cautionary review of negative health and safety effects

BA Roberts - Western journal of emergency medicine, 2019 - ncbi.nlm.nih.gov
Cannabis legalization has led to significant health consequences, particularly to patients in
emergency departments and hospitals in Colorado. The most concerning include psychosis …

Spice/K2 drugs–more than innocent substitutes for marijuana

JB Zawilska, J Wojcieszak - International Journal of …, 2014 - academic.oup.com
Smokeable herbal mixtures containing synthetic agonists of cannabinoid receptors, known
under brand names such as Spice, K2 and Kronic, represent a relatively new type of …