[HTML][HTML] Neurometabolite differences in Autism as assessed with Magnetic Resonance Spectroscopy: A systematic review and meta-analysis

AR Thomson, D Pasanta, T Arichi, NA Puts - Neuroscience & Biobehavioral …, 2024 - Elsevier
Abstract 1 H-Magnetic Resonance Spectroscopy (MRS) is a non-invasive technique that can
be used to quantify the concentrations of metabolites in the brain in vivo. MRS findings in the …

Comparison of seven modelling algorithms for γ‐aminobutyric acid–edited proton magnetic resonance spectroscopy

AR Craven, PK Bhattacharyya, WT Clarke… - NMR in …, 2022 - Wiley Online Library
Edited MRS sequences are widely used for studying γ‐aminobutyric acid (GABA) in the
human brain. Several algorithms are available for modelling these data, deriving metabolite …

MR‐Nucleomics: The study of pathological cellular processes with multinuclear magnetic resonance spectroscopy and imaging in vivo

P Sun, Z Wu, L Lin, G Hu, X Zhang… - NMR in …, 2023 - Wiley Online Library
Clinical medicine has experienced a rapid development in recent decades, during which
therapies targeting specific cellular signaling pathways, or specific cell surface receptors …

GABA and glutamate in pediatric migraine

T Bell, M Stokoe, A Khaira, M Webb, M Noel… - Pain, 2021 - journals.lww.com
Migraine is one of the top 5 most prevalent childhood diseases; however, effective treatment
strategies for pediatric migraine are limited. For example, standard adult pharmaceutical …

Macromolecule suppressed GABA levels show no relationship with age in a pediatric sample

T Bell, M Stokoe, AD Harris - Scientific Reports, 2021 - nature.com
The inhibitory neurotransmitter γ-Aminobutyric acid (GABA) plays a crucial role in cortical
development. Therefore, characterizing changes in GABA levels during development has …

[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease

AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

Recurrent inhibition refines mental templates to optimize perceptual decisions

K Jia, M Wang, C Steinwurzel, JJ Ziminski, Y Xi… - Science …, 2024 - science.org
Translating sensory inputs to perceptual decisions relies on building internal
representations of features critical for solving complex tasks. Yet, we still lack a mechanistic …

Increase in ACC GABA+ levels correlate with decrease in migraine frequency, intensity and disability over time

AL Peek, AM Leaver, S Foster, NA Puts… - The journal of headache …, 2021 - Springer
Background An imbalance between inhibitory and excitatory neurometabolites has been
implicated in chronic pain. Prior work identified elevated levels of Gamma-aminobutyric …

Chronic 3, 4-Methylenedioxymethamphetamine (MDMA) use is related to glutamate and GABA concentrations in the striatum but not the anterior cingulate cortex

J Zimmermann, N Zölch, R Coray… - International Journal …, 2023 - academic.oup.com
Abstract Background 3, 4-Methylenedioxymethamphetamine (MDMA) is a widely used
recreational substance inducing acute release of serotonin. Previous studies in chronic …

Unlocking the link: how hippocampal glutathione–glutamate coupling predicts cognitive impairment in multiple sclerosis patients

F Li, W Zong, C Xin, F Ren, N Li, H Li, X Li, L Wu… - Cerebral …, 2024 - academic.oup.com
Cognitive impairment is a common symptom of multiple sclerosis and profoundly impacts
quality of life. Glutathione (GSH) and glutamate (Glu) are tightly linked in the brain …