Updates on recent clinical assessment of commercial chronic wound care products

A Sharma, D Sharma, F Zhao - Advanced Healthcare Materials, 2023 - Wiley Online Library
Impaired wound healing after trauma, disorders, and surgeries impact millions of people
globally every year. Dysregulation in orchestrated healing mechanisms and underlying …

3D bioprinting of functional skin substitutes: From current achievements to future goals

PG Manita, I Garcia-Orue, E Santos-Vizcaino… - Pharmaceuticals, 2021 - mdpi.com
The aim of this review is to present 3D bioprinting of skin substitutes as an efficient approach
of managing skin injuries. From a clinical point of view, classic treatments only provide …

Application of amniotic membrane in skin regeneration

N Fitriani, G Wilar, AC Narsa, AFA Mohammed… - Pharmaceutics, 2023 - mdpi.com
Amniotic membrane (AM) is an avascular structure composed of three different layers, which
contain collagen, extracellular matrix, and biologically active cells (stem cells). Collagen, a …

Nonpharmacological management of diabetic foot ulcers: an update

I Eleftheriadou, G Samakidou… - … Journal of Lower …, 2021 - journals.sagepub.com
Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes mellitus that
is associated with increased morbidity and mortality, as well as substantial economic burden …

A multicenter, randomized, controlled, clinical trial evaluating dehydrated human amniotic membrane in the treatment of venous leg ulcers

TE Serena, DP Orgill, DG Armstrong… - Plastic and …, 2022 - journals.lww.com
Background: This randomized controlled trial evaluated the safety and effectiveness of
weekly and biweekly applications of dehydrated human amnion and chorion allograft …

Improving Diabetic Wound Healing Outcomes with Topical Growth Factor Therapies: Systematic Review and Network Meta-analysis of Randomised-controlled Trials

AYW Wong, NMF Hooi, BSY Yeo… - The Journal of …, 2024 - academic.oup.com
Context Diabetes mellitus is associated with morbid complications such as diabetic foot
ulcers (DFUs) that may lead to amputations or mortality if not managed adequately …

[HTML][HTML] Topical biological agents as adjuncts to improve wound healing in chronic diabetic wounds: a systematic review of clinical evidence and future directions

AYW Wong, BSY Ong, ARYB Lee, AS Mai… - Cureus, 2022 - ncbi.nlm.nih.gov
Diabetes is a leading chronic illness in the modern world and 19-34% develop chronic
diabetic foot ulcers (DFUs) in their lifetime, often necessitating amputation. The reduction in …

A multicentre clinical trial evaluating the outcomes of two application regimens of a unique keratin‐based graft in the treatment of Wagner grade one non‐healing …

DG Armstrong, DP Orgill, RD Galiano… - International wound …, 2024 - Wiley Online Library
Diabetic foot complications that lead to lower extremity amputations pose a significant
challenge to the entire global health system. In this multicentre clinical trial, 26 patients with …

Use of a purified reconstituted bilayer matrix in the management of chronic diabetic foot ulcers improves patient outcomes vs standard of care: results of a prospective …

DG Armstrong, DP Orgill, RD Galiano… - International wound …, 2022 - Wiley Online Library
Diabetic foot infections continue to be a major challenge for health care delivery systems.
Following encouraging results from a pilot study using a novel purified reconstituted bilayer …

A dehydrated, aseptically-processed human amnion/chorion allograft accelerates healing in a delayed murine excisional wound model

D Dolivo, P Xie, C Hou, A Phipps, T Mustoe… - Experimental Cell …, 2021 - Elsevier
Since chronic, non-healing wounds represent an increasing source of economic and
temporal burden for patients who suffer from them and healthcare professionals that treat …