Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease
During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …
many populations. While uric acid is usually discussed in the context of gout …
The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors
N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a scientific workshop organized by the National Kidney …
Urate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome,
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …
but its relationship to kidney disease, cardiovascular disease, and diabetes remains …
[HTML][HTML] Biochemical and clinical impact of organic uremic retention solutes: a comprehensive update
R Vanholder, A Pletinck, E Schepers, G Glorieux - Toxins, 2018 - mdpi.com
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …
individual uremic retention solutes and groups of solutes is summarized. We classified these …
Uric acid in metabolic syndrome: from an innocent bystander to a central player
M Kanbay, T Jensen, Y Solak, M Le… - European journal of …, 2016 - Elsevier
Uric acid, once viewed as an inert metabolic end-product of purine metabolism, has been
recently incriminated in a number of chronic disease states, including hypertension …
recently incriminated in a number of chronic disease states, including hypertension …
Uric acid and chronic kidney disease: which is chasing which?
RJ Johnson, T Nakagawa, D Jalal… - Nephrology Dialysis …, 2013 - academic.oup.com
Serum uric acid is commonly elevated in subjects with chronic kidney disease (CKD), but
was historically viewed as an issue of limited interest. Recently, uric acid has been …
was historically viewed as an issue of limited interest. Recently, uric acid has been …
Oxidative stress, anti‐oxidant therapies and chronic kidney disease
Chronic kidney disease (CKD) is a common and serious problem that adversely affects
human health, limits longevity and increases costs to health‐care systems worldwide. Its …
human health, limits longevity and increases costs to health‐care systems worldwide. Its …
The role of uric acid in the pathogenesis of human cardiovascular disease
Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly
considered a true risk factor. Recent studies suggest that uric acid is biologically active and …
considered a true risk factor. Recent studies suggest that uric acid is biologically active and …
Sugar, uric acid, and the etiology of diabetes and obesity
The intake of added sugars, such as from table sugar (sucrose) and high-fructose corn syrup
has increased dramatically in the last hundred years and correlates closely with the rise in …
has increased dramatically in the last hundred years and correlates closely with the rise in …
[HTML][HTML] Hyperuricemia and endothelial function: From molecular background to clinical perspectives
T Maruhashi, I Hisatome, Y Kihara, Y Higashi - Atherosclerosis, 2018 - Elsevier
Uric acid is the end product of purine metabolism catalyzed by xanthine oxidase in humans.
In the process of purine metabolism, reactive oxygen species, including superoxide, are …
In the process of purine metabolism, reactive oxygen species, including superoxide, are …