Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …

Iron is a versatile redox-active catalyst and a required cofactor within a diverse array of
biological processes. To almost all organisms, iron is both essential and potentially toxic …

Manganese is a critical micronutrient for cells, serving as an enzyme cofactor and protecting
against oxidative stress. Yet, manganese is toxic in excess and little is known about its …

Summary The Bacillus subtilis MntR metalloregulatory protein senses manganese, an
essential element required for central metabolism, oxidative stress resistance and …

Early epidemiological studies implicated manganese (Mn) as a possible caries-promoting
agent, while laboratory studies have indicated that manganese stimulates the expression of …

ABSTRACT NADH oxidase (Nox) is a flavin-containing enzyme used by Streptococcus
mutans to reduce dissolved oxygen encountered during growth in the oral cavity. In this …

The genome of Mycobacterium tuberculosis, the causative agent of tuberculosis, encodes a
large number of putative transcriptional regulators. However, the identity and target genes of …

Pathogenic streptococci require manganese for survival in the host. In response to invading
pathogens, the host recruits nutritional immune effectors at infection sites to withhold …

Iron, an essential element for microorganisms, functions as a vital cofactor in a wide variety
of key metabolic processes. On the other hand, excess iron may have toxic effects on …

Given the central role of transition metal ions in a variety of biochemical processes, the
colonization, survival, and proliferation of a bacterium within a host hinges upon its ability to …