Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

PR Dandawate, D Subramaniam, RA Jensen… - Seminars in cancer …, 2016 - Elsevier
Breast cancer is the most common form of cancer diagnosed in women worldwide and the
second leading cause of cancer-related deaths in the USA. Despite the development of …

Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment

P Basnet, N Skalko-Basnet - Molecules, 2011 - mdpi.com
Oxidative damage and inflammation have been pointed out in preclinical studies as the root
cause of cancer and other chronic diseases such as diabetes, hypertension, Alzheimer's …

[PDF][PDF] Curcumin and curcuminoids in quest for medicinal status

G Grynkiewicz, P Ślifirski - Acta Biochimica Polonica, 2012 - frontierspartnerships.org
Curcumin, known for thousands of years as an Ayurvedic medicine, and popular as a spice
in Asian cuisine, has undergone in recent times remarkable transformation into a drug …

Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects

H Khan, H Ullah, SM Nabavi - Food and Chemical Toxicology, 2019 - Elsevier
The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management

Y Henrotin, F Priem, A Mobasheri - Springerplus, 2013 - Springer
The management of osteoarthritis represents a real challenge. This complex and multi-
factorial disease evolves over decades and requires not only the alleviation of symptoms, ie …

Targeting cancer stem cells by curcumin and clinical applications

Y Li, T Zhang - Cancer letters, 2014 - Elsevier
Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an
Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and …

The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness

B Bao, AS Azmi, S Ali, A Ahmad, Y Li… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Hypoxia is one of the fundamental biological phenomena that are intricately associated with
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …

Curcumin decreases malignant characteristics of glioblastoma stem cells via induction of reactive oxygen species

ZC Gersey, GA Rodriguez, E Barbarite, A Sanchez… - BMC cancer, 2017 - Springer
Abstract Background Glioblastoma Multiforme (GBM) is the most common and lethal form of
primary brain tumor in adults. Following standard treatment of surgery, radiation and …

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

P Rajendran, E Ho, DE Williams, RH Dashwood - Clinical epigenetics, 2011 - Springer
Genomic instability is a common feature of cancer etiology. This provides an avenue for
therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA …