To Ub or not to Ub: a regulatory question in TGF-β signaling

J Liu, J Jin, T Liang, XH Feng - Trends in Biochemical Sciences, 2022 - cell.com
The transforming growth factor β (TGF-β) superfamily controls a wide spectrum of biological
processes in metazoans, including cell proliferation, apoptosis, differentiation, cell-fate …

E3 ubiquitin ligases: the operators of the ubiquitin code that regulates the RLR and cGAS-STING pathways

L Ji, Y Wang, L Zhou, J Lu, S Bao, Q Shen… - International journal of …, 2022 - mdpi.com
The outbreaks caused by RNA and DNA viruses, such as SARS-CoV-2 and monkeypox,
pose serious threats to human health. The RLR and cGAS-STING pathways contain major …

Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease

F Han, S Wu, Y Dong, Y Liu, B Sun, L Chen - Journal of Translational …, 2024 - Springer
Disturbance in mitochondrial homeostasis within proximal tubules is a critical characteristic
associated with diabetic kidney disease (DKD). CaMKKβ/AMPK signaling plays an important …

[HTML][HTML] The prodomain of bone morphogenetic protein 2 promotes dimerization and cleavage of BMP6 homodimers and BMP2/6 heterodimers

P Chauhan, Y Xue, HS Kim, AL Fisher, JL Babitt… - Journal of Biological …, 2024 - Elsevier
Abstract Bone morphogenetic protein 2 (BMP2) and BMP6 are key regulators of systemic
iron homeostasis. All BMPs are generated as inactive precursor proteins that dimerize and …

[HTML][HTML] New aspects of TGF-β superfamily signaling in development and disease (2022 FASEB meeting review)

SJ Newfeld, MB O'Connor - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
Abstract The 13th Federation of American Societies for Experimental Biology (FASEB)
Summer Research Conference,“TGF-β superfamily signaling in development and disease” …