The brain neuronal systems defined by the neurotransmitter dopamine (DA) have since long
a recognized role in the regulation of motor functions. More recently, converging evidence …

Tobacco smoke consists of thousands of compounds including nicotine. Many constituents
have known toxicity to the brain, cardiovascular, and pulmonary systems. Nicotine, on the …

The variability in phenotypic presentations and the lack of consistency of genetic
associations in mental illnesses remain a major challenge in molecular psychiatry. Recently …

Background Executive functioning (EF) refers to the set of neurocognitive processes that
facilitate novel problem solving, modification of behavior in response to environmental …

Parkinson's disease is associated with multiple cognitive impairments and increased risk of
dementia, but the extent of these deficits varies widely among patients. The ICICLE-PD study …

Individual differences in cognitive performance increase from early to late adulthood, likely
reflecting influences of a multitude of factors. We hypothesize that losses in neurochemical …

We demonstrate that common genetic polymorphisms contribute to the increasing
heterogeneity of cognitive functioning in old age. We assess two common Val/Met …

The failure in the discovery of etiology of psychiatric diseases, despite extensive genetic
studies, has directed the attention of neuroscientists to the contribution of epigenetic …

Cognitive deficits are critical determinants of schizophrenia morbidity. In this review, we offer
a mechanistic perspective regarding schizophrenia-related changes observed in prefrontal …

Individual differences in working memory (WM) performance have rarely been related to
individual differences in the functional responsivity of the WM brain network. By neglecting …