[HTML][HTML] Stress-associated molecular and cellular hippocampal mechanisms common for epilepsy and comorbid depressive disorders

NV Gulyaeva - Biochemistry (Moscow), 2021 - Springer
The review discusses molecular and cellular mechanisms common to the temporal lobe
epileptogenesis/epilepsy and depressive disorders. Comorbid temporal lobe epilepsy and …

[HTML][HTML] Post-stroke neuropsychiatric complications: types, pathogenesis, and therapeutic intervention

J Zhou, Y Fangma, Z Chen, Y Zheng - Aging and disease, 2023 - ncbi.nlm.nih.gov
Almost all stroke survivors suffer physical disabilities and neuropsychiatric disturbances,
which can be briefly divided into post-stroke neurological diseases and post-stroke …

[HTML][HTML] ECoG spiking activity and signal dimension are early predictive measures of epileptogenesis in a translational mouse model of traumatic brain injury

R Di Sapia, M Rizzi, F Moro, I Lisi, A Caccamo… - Neurobiology of …, 2023 - Elsevier
The latency between traumatic brain injury (TBI) and the onset of epilepsy (PTE) represents
an opportunity for counteracting epileptogenesis. Antiepileptogenesis trials are hampered …

[HTML][HTML] Elevated serum cortisol levels in patients with focal epilepsy, depression, and comorbid epilepsy and depression

TA Druzhkova, AA Yakovlev, FK Rider… - International Journal of …, 2022 - mdpi.com
Background: The hypothalamic-pituitary-adrenal (HPA) axis, inflammatory processes and
neurotrophic factor systems are involved in pathogenesis of both epilepsy and depressive …

Microglia as a game changer in epilepsy comorbid depression

W Wen, J Zhou, C Zhan, J Wang - Molecular Neurobiology, 2024 - Springer
As one of the most common neurological diseases, epilepsy is often accompanied by
psychiatric disorders. Depression is the most universal comorbidity of epilepsy, especially in …

[HTML][HTML] The ketogenic diet revisited: beyond ketones

J Sourbron, K Thevissen, L Lagae - Frontiers in neurology, 2021 - frontiersin.org
Epilepsy is a neurological disease characterized by seizures, which affects up to 65 million
people worldwide (1). About two-thirds of patients with epilepsy are able to achieve seizure …

Brain anomalies in early psychosis: From secondary to primary psychosis

A Iftimovici, B Chaumette, E Duchesnay… - … & Biobehavioral Reviews, 2022 - Elsevier
Brain anomalies are frequently found in early psychoses. Although they may remain
undetected for many years, their interpretation is critical for differential diagnosis. In …

Anticonvulsant Effect of Asparagus racemosus Willd. in a Mouse Model of Catamenial Epilepsy

P Pahwa, T Singh, RK Goel - Neurochemical research, 2022 - Springer
Abstract Asparagus racemosus Willd.(Family Liliaceae), also known as female reproductive
tonic, is traditionally used across the Sub-Himalayan region in Uttarakhand, India for …

Seizure-related stress and arousal responses mediate a relationship between anxiety trait and state in epilepsy

H Nakamura, G Sugihara, K Hara, M Inaji, M Noha… - Epilepsy & Behavior, 2023 - Elsevier
Background Epilepsy causes substantial psychological distress and anxiety, primarily due to
seizures. However, the impact of stress responses and changes in arousal and their …

[HTML][HTML] Antidepressant drugs for seizures and epilepsy: Where do we stand?

M Tallarico, M Pisano, A Leo, E Russo… - Current …, 2023 - ncbi.nlm.nih.gov
People with epilepsy (PWE) are more likely to develop depression and both these complex
chronic diseases greatly affect health-related quality of life (QOL). This comorbidity …