[HTML][HTML] Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy

Y Chen, S Shi, Y Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …

A comprehensive review of the classification, sources, biosynthesis, and biological properties of hydroxybenzoic and hydroxycinnamic acids

APG da Silva, WG Sganzerla, OD John… - Phytochemistry …, 2023 - Springer
Simple phenolic acids are considered the most common and widely studied bioactive
compounds belonging to plants' secondary metabolites. The simple phenolic acids can be …

Naringenin regulates doxorubicin-induced liver dysfunction: impact on oxidative stress and inflammation

AF Wali, S Rashid, SM Rashid, MA Ansari, MR Khan… - Plants, 2020 - mdpi.com
Doxorubicin (Dox) is an operational and largely used anticancer drug, used to treat an array
of malignancies. Nonetheless, its beneficial use is constrained due to its renal and …

Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis

SE Owumi, DO Lewu, UO Arunsi… - Human & experimental …, 2021 - journals.sagepub.com
Doxorubicin is an effective anti-neoplastic agent; the reported toxicities of DOX limit its use.
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …

Curcumin ameliorates doxorubicin-induced cardiotoxicity and hepatotoxicity via suppressing oxidative stress and modulating iNOS, NF-κB, and TNF-α in rats

G Ibrahim Fouad, KA Ahmed - Cardiovascular toxicology, 2022 - Springer
Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …

[HTML][HTML] N-Acetylcysteine may exert hepatoprotective effect by regulating Meteorin-Like levels in Adriamycin-induced liver injury

S Kaya, T Yalcın, A Tektemur, T Kuloğlu - Cell Stress and Chaperones, 2023 - Elsevier
Adriamycin (ADR) is an important chemotherapeutic drug, but it has serious side effects
such as hepatotoxicity. This study aimed to evaluate whether N-acetylcysteine (NAC) has …

99mTc-Doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent

WI El-Ghareb, MM Swidan, IT Ibrahim… - International journal of …, 2020 - Elsevier
The development of cancer theranostic nanomedicines is recommended to concurrently
achieve and evaluate the therapeutic benefit and progress. The current work aims to …

Thymoquinone is a protective agent that reduces the negative effects of doxorubicin in rat testis

E Öztürk, E Kaymak, AT Akin… - Human & …, 2020 - journals.sagepub.com
Background: Doxorubicin (DOX) is used for treatment of many cancer types. Thymoquinone
(THQ) is a powerful antioxidant agent used for reducing side effects of several drugs. The …

Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis

AT Akin, E Öztürk, E Kaymak… - Anatomia, histologia …, 2021 - Wiley Online Library
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …

Systematic evaluations of doxorubicin-induced toxicity in rats based on metabolomics

C Geng, C Cui, C Wang, S Lu, M Zhang, D Chen… - ACS …, 2020 - ACS Publications
Doxorubicin (DOX) is widely used to treat solid tumors, but its use is limited by its severe
cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Metabolomic studies on DOX …