Mechanisms by which the gut microbiota influences cytokine production and modulates host inflammatory responses
The gastrointestinal tract encounters a wide variety of microorganisms, including beneficial
symbionts, pathobionts, and pathogens. Recent evidence has shown that the gut microbiota …
symbionts, pathobionts, and pathogens. Recent evidence has shown that the gut microbiota …
An overview of host‐derived molecules that interact with gut microbiota
C Zhang, H Liu, L Sun, Y Wang, X Chen, J Du… - Imeta, 2023 - Wiley Online Library
The gut microbiota comprises bacteria, archaea, fungi, protists, and viruses that live together
and interact with each other and with host cells. A stable gut microbiota is vital for regulating …
and interact with each other and with host cells. A stable gut microbiota is vital for regulating …
il1r2 blockade suppresses breast tumorigenesis and progression by impairing usp15‐dependent bmi1 stability
L Zhang, J Qiang, X Yang, D Wang… - Advanced …, 2020 - Wiley Online Library
Breast tumor initiating cells (BTICs) with ALDH+ CD24− CD44+ phenotype are the most
tumorigenic and invasive cell population in breast cancer. However, the molecular …
tumorigenic and invasive cell population in breast cancer. However, the molecular …
Regulation of IL-1 signaling by the decoy receptor IL-1R2
T Schlüter, C Schelmbauer, K Karram… - Journal of Molecular …, 2018 - Springer
The pleiotropic cytokine IL-1 mediates its biological functions via association with the
signaling receptor IL-1R1. Despite an apparent simplicity in IL-1 signaling activation …
signaling receptor IL-1R1. Despite an apparent simplicity in IL-1 signaling activation …
Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection
AD Smith, ED Foss, I Zhang, JL Hastie, NP Giordano… - PLoS …, 2019 - journals.plos.org
Clostridium difficile (Cd) infection (CDI) typically occurs after antibiotic usage perturbs the
gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their …
gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their …
Trilobatin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via the NF-κB pathway and alterations in gut microbiota
N Wang, Z Li, L Cao, Z Cui - Plos one, 2024 - journals.plos.org
Objective This study aimed to evaluate the effects of trilobatin (TLB) on dextran sulfate
sodium (DSS)-induced ulcerative colitis (UC) in mice and further explore the underlying …
sodium (DSS)-induced ulcerative colitis (UC) in mice and further explore the underlying …
Negative regulator IL-1 receptor 2 (IL-1R2) and its roles in immune regulation of autoimmune diseases
Y Zhang, K Liu, M Guo, Y Yang, H Zhang - International …, 2024 - Elsevier
The decoy receptor interleukin 1 receptor 2 (IL-1R2), also known as CD121b, has different
forms: membrane-bound (mIL-1R2), soluble secreted (ssIL-1R2), shedded (shIL-1R2) …
forms: membrane-bound (mIL-1R2), soluble secreted (ssIL-1R2), shedded (shIL-1R2) …
Mulberry juice freeze-dried powder attenuates the disease severity by the maintaining of colon mucosa in mice with DSS-induced acute colitis
Y Wang, T Hatabu - Bioscience, Biotechnology, and …, 2019 - academic.oup.com
This study aimed to evaluate the microbial compositions and gene expression related to
inflammation in dextran sodium sulfate (DSS)-induced acute colitis and the effect of mulberry …
inflammation in dextran sodium sulfate (DSS)-induced acute colitis and the effect of mulberry …
Complement C3 deficient mice show more severe imiquimod-induced psoriasiform dermatitis than wild-type mice regardless of the commensal microbiota
MA Murayama - Experimental Animals, 2024 - jstage.jst.go.jp
Abstract 1 The complement active product, C3a, and the receptor C3aR comprise an axis
that exerts 2 various biological functions, such as protection against infection. C3a is highly …
that exerts 2 various biological functions, such as protection against infection. C3a is highly …
Nicotine treatment shows the therapeutic effect for imiquimod-induced psoriasiform dermatitis in alpha 7-nicotinic acetylcholine receptor-independent manner
MA MURAYAMA - Translational and Regulatory Sciences, 2022 - jstage.jst.go.jp
The neurotransmitter acetylcholine (ACh) stimulates nicotinic ACh receptors (nAChRs)
expressed in both excitable and non-excitable cells. Cholinergic signaling in non-excitable …
expressed in both excitable and non-excitable cells. Cholinergic signaling in non-excitable …