Poly-γ-glutamic acid nanoparticles as adjuvant and antigen carrier system for cancer vaccination

V Mohammadzadeh, N Rahiman, H Cabral… - Journal of Controlled …, 2023 - Elsevier
Vaccination is an innovative strategy for cancer treatment by leveraging various components
of the patients' immunity to boost an anti-tumor immune response. Rationally designed …

Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy

J Jia, Y Zhang, Y Xin, C Jiang, B Yan, S Zhai - Frontiers in oncology, 2018 - frontiersin.org
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …

A review of mechanistic insight and application of pH-sensitive liposomes in drug delivery

SR Paliwal, R Paliwal, SP Vyas - Drug delivery, 2015 - Taylor & Francis
The pH-sensitive liposomes have been extensively used as an alternative to conventional
liposomes in effective intracellular delivery of therapeutics/antigen/DNA/diagnostics to …

Biodegradable nanoparticles as vaccine adjuvants and delivery systems: regulation of immune responses by nanoparticle-based vaccine

T Akagi, M Baba, M Akashi - Polymers in nanomedicine, 2012 - Springer
Polymeric nano-and microparticles have recently been shown to possess significant
potential as drug delivery systems. In particular, the use of biodegradable polymeric …

Improvement of different vaccine delivery systems for cancer therapy

A Bolhassani, S Safaiyan, S Rafati - Molecular cancer, 2011 - Springer
Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …

Nanoparticle delivery systems in cancer vaccines

Y Krishnamachari, SM Geary, CD Lemke… - Pharmaceutical …, 2011 - Springer
Therapeutic strategies that involve the manipulation of the host's immune system are gaining
momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively …

A liposome-based antigen delivery system using pH-sensitive fusogenic polymers for cancer immunotherapy

E Yuba, A Harada, Y Sakanishi, S Watarai, K Kono - Biomaterials, 2013 - Elsevier
Highly pH-sensitive liposomes that deliver antigenic molecules into cytosol through fusion
with or destabilization of endosome were prepared by surface modification of egg yolk …

Polymeric particles in vaccine delivery

AC Rice-Ficht, AM Arenas-Gamboa… - Current opinion in …, 2010 - Elsevier
The tremendous power of the particulate vaccine delivery system has only recently been
recognized and employed strategically in vaccine design. The entrapment of antigen in …

Drug delivery nanoparticles formulation and characterization

Y Pathak, D Thassu - Drugs and Pharmaceutical Science …, 2009 - api.taylorfrancis.com
Modern nanotechnology is an emerging and dynamic field. It is multidisciplinary in nature. It
appears that Mother Nature was the first scientist offering nanoscale materials abundantly …

Nanoparticle‐based manipulation of antigen‐presenting cells for cancer immunotherapy

RH Fang, AV Kroll, L Zhang - Small, 2015 - Wiley Online Library
Immunotherapeutic approaches for treating cancer overall have been receiving a
considerable amount of interest due to the recent approval of several clinical formulations …