Advances in cancer treatments have improved clinical outcomes, leading to an increasing
population of cancer survivors. However, this success is associated with high rates of short …

Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

Pediatric brain tumor survivors require coordinated interdisciplinary care, ongoing
evaluation and management of late effects, and timely interventions focused on mitigating …

Purpose AcSé-ESMART is a European multicentre, proof-of-concept multiarm phase I/II
platform trial in paediatric patients with relapsed/refractory cancer. Arm G assessed the …

Background Childhood cancer survivors are at risk for developing long‐term adverse health
outcomes. To identify the risk of and risk factors for specific health outcomes, well …

Background Childhood cancer survivors are at risk of subsequent gliomas and
meningiomas, but the risks beyond age 40 years are uncertain. We quantified these risks in …

PURPOSE Heart failure (HF) is a potentially life-threatening complication of treatment for
childhood cancer. We evaluated the risk and risk factors for HF in a large European study of …

Survivors of childhood cancer experience substantial premature mortality; in the British
Childhood Cancer Survivor Study (BCCSS) cohort, by 50 years from diagnosis 30% of 5 …

Progress in medicine has increased the survival time of children suffering from cancer;>
80% of patients survive for at least 5 years from the end of treatment. However, there are late …

Background Second malignant neoplasms and cardiotoxicity are among the most serious
and frequent adverse health outcomes experienced by childhood and adolescent cancer …