BACKGROUND A time lapse system (TLS) is utilized in some fertility clinics with the aim of
predicting embryo viability and chance of live birth during IVF. It has been hypothesized that …

Trisomic and monosomic (aneuploid) embryos account for at least 10% of human
pregnancies and, for women nearing the end of their reproductive lifespan, the incidence …

Background Advances in embryo culture media have led to a shift in in vitro fertilisation (IVF)
practice from cleavage‐stage embryo transfer to blastocyst‐stage embryo transfer. The …

Background Single embryo transfer (SET) remains underutilized as a strategy to reduce
multiple gestation risk in IVF, and its overall lower pregnancy rate underscores the need for …

Chromosome instability is a hallmark of tumorigenesis. This study establishes that
chromosome instability is also common during early human embryogenesis. A new array …

BACKGROUND Preimplantation genetic screening (PGS) has increasingly been used in the
past decade. Here we present a systematic review and meta-analysis of RCTs on the effect …

Objective To assess the relationship between maternal age, chromosome abnormality,
implantation, and pregnancy loss. Design Multicenter retrospective study. Setting IVF …

The Imperative of Responsible Innovation in Reproductive Medicine Page 1 Sounding Board The
new england journal of medicine n engl j med 385;22 nejm.org November 25, 2021 2096 The …

Objective To study whether preimplantation genetic screening with comprehensive
chromosome screening (PGS-CCS) improves clinical implantation rates (IR) and sustained …

Recurrent miscarriage is a common pathology fond in 1% to 5% of reproductively active
couples. This chapter discusses the possible causes of recurrent miscarriage, and …