Diagnosis of patients with Lynch syndrome lacking the Amsterdam II or Bethesda criteria

MA Trujillo-Rojas, ML Ayala-Madrigal… - Hereditary Cancer in …, 2023 - Springer
Abstract Background Lynch Syndrome (LS) is an autosomal dominant inheritance disorder
characterized by genetic predisposition to develop cancer, caused by pathogenic variants in …

[HTML][HTML] Microsatellite Status Detection of Colorectal Cancer: Evaluation of Inconsistency between PCR and IHC

J Chen, Q Yan, J Sun, Q Wang, Y Tao, D Xiao… - Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: An essential component of precision medical treatment for colorectal cancer
(CRC) is the use of microsatellite state in combination with polymerase chain reaction (PCR) …

Microsatellite instability screening in colorectal carcinoma: immunohistochemical analysis of MMR proteins in correlation with clinicopathological features and Ki-67 …

NN Yassen, DM Abouelfadl, NF Abbas… - Bulletin of the National …, 2023 - Springer
Background Defects in mismatch repair (MMR) system or microsatellite instability (MSI) and
detected in colorectal carcinoma (CRC), both in sporadic and more frequently in hereditary …

Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques

S Deycmar, BJ Johnson, K Ray, GW Schaaf… - Journal of translational …, 2024 - Springer
Background Naturally occurring colorectal cancers (CRC) in rhesus macaques share many
features with their human counterparts and are useful models for cancer immunotherapy; but …

Clinical, Pathological, and Molecular Characteristics in Colorectal Cancer

S Dedieu, O Bouché - Cancers, 2022 - mdpi.com
Carcinogenesis steps have commonly involved the growth and expansion of adenomatous
polyps from normal colorectal epithelium to adenoma through a multistep process of several …

[PDF][PDF] To Correlate the Expression of KRAS and BRAF V600e with Histological Grades and Variants in Tissue Samples of Colorectal Carcinoma

H Wasti, S Shawana, S Shafique… - Journal of …, 2023 - pdfs.semanticscholar.org
RESULTS Fifty-one cases of CRC were analyzed for immunoexpression of KRAS and BRAF
V600E. The age of the patients ranged from 14 to 85 years, with a mean age of 60.96 years …