During pregnancy, the mother must adapt her body systems to support nutrient and oxygen
supply for growth of the baby in utero and during the subsequent lactation. These include …

The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

The principal role of prolactin in mammals is the regulation of lactation. Prolactin is a
hormone that is mainly synthesized and secreted by lactotroph cells in the anterior pituitary …

The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

Prolactin is a hormone that is mainly secreted by lactotroph cells of the anterior pituitary
gland, and is involved in many biological processes including lactation and reproduction …

A woman's breast cancer risk is affected by her reproductive history. The hormonal milieu
also influences the course of the disease. The female reproductive hormones, estrogens …

Breast cancer manifests itself in the mammary epithelium, yet there is a growing recognition
that mammary stromal cells also play an important role in tumorigenesis. During its …

The endocrine system coordinates development of the mammary gland with reproductive
development and the demand of the offspring for milk. Three categories of hormones are …

Unique developmental features during puberty, pregnancy, lactation and post-lactation
make the mammary gland a prime object to explore genetic circuits that control the …

Part of how the mammary gland fulfills its function of producing and delivering adequate
amounts of milk is by forming an extensive tree-like network of branched ducts from a …