The classical target organs for parathyroid hormone (PTH) are the bone and kidneys. In
uremia, however, numerous studies have shown that PTH may also affect the function of a …

Benefits of calcitriol therapy in uremic dogs and cats are considered by discussing
mechanisms underlying the positive responses to a survey relating to this treatment. The …

Abnormal glucose metabolism and a high prevalence of diabetes have been reported in
patients with primary and secondary hyperparathyroidism. We hypothesize that plasma …

Excess PTH in CRF induces pulmonary calcification, pulmonary hypertension and right
ventricular hypertrophy. Calcification of the lungs occurs in chronic renal failure (CRF) and …

It has been suggested that a sustained rise in resting levels of cytosolic calcium [Ca2+] i of
pancreatic islets is responsible for impaired insulin secretion in chronic renal failure (CRF) …

Excess parathyroid hormone (PTH) in presence or absence of chronic renal failure impairs
insulin release from pancreatic islets. This abnormality has been attributed to PTH-induced …

Introduction: Glycoxidative stress is essential for linking glucose disturbances and
cardiovascular diseases. Unfortunately, contemporary antidiabetic drugs do not have an …

Phosphate depletion impairs insulin secretion by pancreatic islets. Phosphate depletion
(PD) is associated with resistance to the peripheral action of insulin and with glucose …

Bone is a classic target tissue for parathyroid hormone (PTH), whose calciotropic effect is
mediated largely via catabolic actions on this tissue. Paradoxically, PTH also exerts anabolic …

Diabetes mellitus is a complex syndrome which is responsible for numerous complications
affecting the whole body. Osteoporosis is regarded as one of the chronic complications of …