Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

Epithelial-mesenchymal transition: Insights into nickel-induced lung diseases

HW Lee, CC Jose, S Cuddapah - Seminars in cancer biology, 2021 - Elsevier
Nickel compounds are environmental toxicants, prevalent in the atmosphere due to their
widespread use in several industrial processes, extensive consumption of nickel containing …

Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis

X Zhao, S Wei, Z Li, C Lin, Z Zhu, D Sun, R Bai… - Cell Death & …, 2019 - nature.com
Silica nanoparticles (SiNPs) have been reported to induce pulmonary fibrosis (PF) with an
unknown mechanism. Recently, the activation of autophagy, a lysosome-dependent cell …

Melatonin relieves liver fibrosis induced by Txnrd3 knockdown and nickel exposure via IRE1/NF-kB/NLRP3 and PERK/TGF-β1 axis activation

Q Liu, Y Sun, Y Zhu, S Qiao, J Cai, Z Zhang - Life sciences, 2022 - Elsevier
Abstract Aims Nickel (Ni) accumulates in the environment due to human activities such as
electroplating, alloy production, stainless steel, Ni‑cadmium batteries and industrial …

Cancer and non-cancer risk concerns from metals in electronic cigarette liquids and aerosols

J Fowles, T Barreau, N Wu - … journal of environmental research and public …, 2020 - mdpi.com
We evaluated metal concentrations in e-liquids and e-aerosols from eight studies and
estimated the range of corresponding cancer and non-cancer risks. Chromium and nickel …

LncRNA MEG3 mediates nickel oxide nanoparticles‐induced pulmonary fibrosis via suppressing TGF‐β1 expression and epithelial‐mesenchymal transition process

H Zhan, X Chang, X Wang, M Yang… - Environmental …, 2021 - Wiley Online Library
Abstract Nickel oxide nanoparticles (NiO NPs) causes pulmonary fibrosis via activating
transforming growth factor‐β1 (TGF‐β1) in rats, but its upstream regulatory mechanisms are …

Toxic effects of low-level long-term inhalation exposures of rats to nickel oxide nanoparticles

MP Sutunkova, SN Solovyeva, IA Minigalieva… - International journal of …, 2019 - mdpi.com
Rats were exposed to nickel oxide nanoparticles (NiO-NP) inhalation at 0.23±0.01 mg/m3
for 4 ha day 5 times a week for up to 10 months. The rat organism responded to this impact …

The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy‐Mediated Lung Inflammation and …

Y Lin, D Tan, Q Kan, Z Xiao… - Mediators of inflammation, 2018 - Wiley Online Library
Our previous study has shown that Chinese medicine, Qingfei Tongluo formula (QTF), has a
significantly therapeutic effect to Mycoplasma pneumoniae (MP) pneumonia (MPP). The aim …

LncRNA AP000487. 1 regulates PRKCB DNA methylation‐mediated TLR4/MyD88/NF‐κB pathway in Nano NiO‐induced collagen formation in BEAS‐2B cells

J Zheng, J Wang, K Li, X Qin, S Li… - Environmental …, 2023 - Wiley Online Library
Abstract Nickel oxide nanoparticles (Nano NiO) have been shown to cause pulmonary
fibrosis; But, the underlying epigenetic mechanisms remain poorly understood. In this study …

Nano NiO induced liver toxicity via activating the NF-κB signaling pathway in rats

F Liu, X Chang, M Tian, A Zhu, L Zou, A Han… - Toxicology …, 2017 - academic.oup.com
Studies have demonstrated that nano NiO could induce liver toxicity in rats, but its
mechanism remains unclear. This study aimed to explore the role of the NF-κB signaling …