Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Calcium phosphate (CaP) materials have many peculiar and intriguing properties. In nature,
CaP is found in nanostructured form embedded in a soft proteic matrix as the main mineral …

Vaccination has a great impact on the prevention and control of infectious diseases.
However, there are still many infectious diseases for which an effective vaccine is missing …

Calcium phosphate/poly (D, L-lactide-co-glycolide)(PLGA) nanoparticles with a diameter
below 200 nm, loaded with either nucleic acids or proteins, were synthesized by a water-in …

Avidin was covalently conjugated to the surface of calcium phosphate nanoparticles, coated
with a thin silica shell and terminated by sulfhydryl groups (diameter of the solid core about …

A versatile drug delivery system based on calcium phosphate/Eudragit®-E100 nanoparticles
with a diameter below 200 nm was realized by a water-in-oil-in-water (W1/O/W2) emulsion …

Nanoparticles can be used as carriers to transport biomolecules like proteins and synthetic
molecules across the cell membrane because many molecules are not able to cross the cell …

The efficient intracellular delivery of (bio) molecules into living cells remains a challenge in
biomedicine. Many biomolecules and synthetic drugs are not able to cross the cell …

The design of polymacrocyclic structures is of high importance for the improvement of
recognition ability to various guests. We present a convenient approach towards two types of …

Penetration through the cell membrane, endosomal escape and nuclear entry are the main
barriers that transfection agents have to overcome. We prepared multi-shell calcium …