Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …
because of their high immunomodulation ability, tropism towards inflamed and injured …
[HTML][HTML] Advances and challenges in stem cell culture
C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …
medicine as well as pharmaceutical and biotechnological applications. They have the …
Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway
X Rong, J Liu, X Yao, T Jiang, Y Wang, F Xie - Stem cell research & …, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are increasingly being applied as a
therapy for liver fibrosis. Exosomes possess similar functions to their parent cells; however …
therapy for liver fibrosis. Exosomes possess similar functions to their parent cells; however …
Liver regeneration—mechanisms and models to clinical application
SJ Forbes, PN Newsome - Nature reviews Gastroenterology & …, 2016 - nature.com
Liver regeneration has been studied for many decades and the mechanisms underlying
regeneration of the normal liver following resection or moderate damage are well described …
regeneration of the normal liver following resection or moderate damage are well described …
Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
Applications of alginate microspheres in therapeutics delivery and cell culture: Past, present and future
D Dhamecha, R Movsas, U Sano, JU Menon - International journal of …, 2019 - Elsevier
Polymers are the backbone of pharmaceutical drug delivery. There are several polymers
with varying properties available today for use in different pharmaceutical applications …
with varying properties available today for use in different pharmaceutical applications …
hucMSC exosome-derived GPX1 is required for the recovery of hepatic oxidant injury
Y Yan, W Jiang, Y Tan, S Zou, H Zhang, F Mao… - Molecular Therapy, 2017 - cell.com
Exosomes are small biological membrane vesicles secreted by various cells, including
mesenchymal stem cells (MSCs). We previously reported that MSC-derived exosomes (MSC …
mesenchymal stem cells (MSCs). We previously reported that MSC-derived exosomes (MSC …
Mesenchymal stromal cells in hepatic fibrosis/cirrhosis: from pathogenesis to treatment
Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …
BMSCs-derived miR-223-containing exosomes contribute to liver protection in experimental autoimmune hepatitis
L Chen, F Lu, D Chen, J Wu, L Xu, M Zheng, H Li… - Molecular …, 2018 - Elsevier
Autoimmune hepatitis is a chronic inflammatory disease in the liver with potential to the
development of liver fibrosis. Recent evidences suggest that bone marrow derived …
development of liver fibrosis. Recent evidences suggest that bone marrow derived …
Biomaterial-assisted regenerative medicine
T Nii, Y Katayama - International journal of molecular sciences, 2021 - mdpi.com
This review aims to show case recent regenerative medicine based on biomaterial
technologies. Regenerative medicine has arousing substantial interest throughout the world …
technologies. Regenerative medicine has arousing substantial interest throughout the world …