Chikungunya virus is widespread throughout the tropics, where it causes recurrent
outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East …

The alphaviruses are a widely distributed group of positive-sense, single stranded, RNA
viruses. These viruses are largely arthropod-borne and can be found on all populated …

To better understand how positive-strand (+) RNA viruses assemble membrane-associated
replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected …

Alphaviruses are emerging positive-stranded RNA viruses which replicate and transcribe
their genomes in membranous organelles formed in the cell cytoplasm. The nonstructural …

Positive-strand RNA viruses replicate their genomes in virus-induced membrane vesicles,
and the resulting RNA replication complexes are a major target for virus control. Nodavirus …

Chikungunya virus (CHIKV) nonstructural protein 1 (nsP1) contains both the N7-guanine
methyltransferase and guanylyltransferase activities and catalyzes the 5′ end cap …

Many alphaviruses, including chikungunya virus (CHIKV) are known human pathogens that
lack specific and effective antivirals or vaccines available. The upstream portion of the …

Chikungunya virus (CHIKV) is a mosquito-transmitted, RNA virus that causes an often-
severe musculoskeletal illness characterized by fever, joint pain, and a range of debilitating …

The search for bioactive compounds in natural products holds promise for discovering new
pharmacologically active molecules. This study explores the anti-inflammatory potential of …

Ross River virus (RRV) and Barmah Forest virus (BFV) are arthritogenic arthropod-borne
viruses (arboviruses) that exhibit generalist host associations and share distributions in …