On the basis of many literature measurements, a critical overview is given on essential
noncovalent interactions in synthetic supramolecular complexes, accompanied by analyses …

Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …

Hydrogen (H)-bonds potentiate diverse cellular functions by facilitating molecular
interactions. The mechanism and the extent to which H-bonds regulate molecular …

As the protein databank (PDB) recently passed the cap of 123 456 structures, it stands more
than ever as an important resource not only to analyze structural features of specific …

Noncovalent interactions are essential for the existence of solid and liquid phases. 1, 2
Traditionally touted as weak forces, quantification of these interactions, which govern the …

This review describes a multidimensional treatment of molecular recognition phenomena
involving aromatic rings in chemical and biological systems. It summarizes new results …

Molecular recognition in biological systems relies on the existence of specific attractive
interactions between two partner molecules. Structure-based drug design seeks to identify …

The cation− π interaction is an attractive noncovalent interaction between a cation and a π
system. Due to the stronger interaction energy than those of the other π interactions, such as …

The development of synthetic host–guest chemistry to investigate and quantify weak, non-
covalent interactions has been key to unraveling the complexity of molecular recognition in …

In the context of drug design, CH··· O hydrogen bonds have received little attention so far,
mostly because they are considered weak relative to other noncovalent interactions such as …