Highlights•The biofilm formation process and its microenvironmental characteristics are
described.•Biofilm microenvironment-responsive nanoparticles for anti-infection are …

The skin is the biggest organ of human body which acts as a protective barrier against
deleterious agents. When this barrier is damaged, the organism promotes the healing …

Microorganisms colonize various ecological niches in the human habitat, as they do in
nature. Predominant forms of multicellular communities called biofilms colonize human …

Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their potent
antibacterial and wound healing properties. Bare AMPs have limited activity following topical …

Ideal epidermal bioelectronics can be used not only for long‐term detection of physiological
signals for disease diagnosis but also for chronic disease treatment. Silk, an animal‐derived …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

Diabetic foot ulcers (DFUs) are a devastating ailment for many diabetic patients with
increasing prevalence and morbidity. The complex pathophysiology of DFU wound …

Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

Wound healing is an essential process to restore tissue integrity after trauma. Large skin
wounds such as burns often heal with hypertrophic scarring and contractures, resulting in …

Biofilm infection is the major concern of medical implants, which often causes progressive
destruction of surrounding tissues and systemic diseases. However, biofilm resistance …