Sugar Sensing and Signaling in Candida albicans and Candida glabrata

M Van Ende, S Wijnants, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida species, such as Candida albicans and Candida glabrata, cause infections at
different host sites because they adapt their metabolism depending on the available …

Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

Role of amino acid metabolism in the virulence of human pathogenic fungi

E Garbe, S Vylkova - Current Clinical Microbiology Reports, 2019 - Springer
Abstract Purpose of the Review The success of Candida albicans, Aspergillus fumigatus,
and Cryptococcus neoformans as fungal pathogens depends on their rapid adaptation to …

From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans

EWL Chow, LM Pang, Y Wang - Pathogens, 2021 - mdpi.com
Candida albicans is a major fungal pathogen of humans, accounting for 15% of nosocomial
infections with an estimated attributable mortality of 47%. C. albicans is usually a benign …

[HTML][HTML] Recent advances in understanding Candida albicans hyphal growth

RA Arkowitz, M Bassilana - F1000Research, 2019 - ncbi.nlm.nih.gov
Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …

Methionine at the heart of anabolism and signaling: perspectives from budding yeast

AS Walvekar, S Laxman - Frontiers in microbiology, 2019 - frontiersin.org
Studies using a fungal model, Saccharomyces cerevisiae, have been instrumental in
advancing our understanding of sulfur metabolism in eukaryotes. Sulfur metabolites …

Raman Imaging of Pathogenic Candida auris: Visualization of Structural Characteristics and Machine-Learning Identification

G Pezzotti, M Kobara, T Asai, T Nakaya… - Frontiers in …, 2021 - frontiersin.org
Invasive fungal infections caused by yeasts of the genus Candida carry high morbidity and
cause systemic infections with high mortality rate in both immunocompetent and …

Conserved and Divergent Functions of the cAMP/PKA Signaling Pathway in Candida albicans and Candida tropicalis

CJ Lin, YL Chen - Journal of Fungi, 2018 - mdpi.com
Fungal species undergo many morphological transitions to adapt to changing environments,
an important quality especially in fungal pathogens. For decades, Candida albicans has …

Essential, deadly, enigmatic: Polyamine metabolism and roles in fungal cells

RO Rocha, RA Wilson - Fungal Biology Reviews, 2019 - Elsevier
Polyamines are essential metabolites found in all organisms. Intracellular polyamine levels
are tightly maintained by biosynthesis, degradation, uptake and excretion processes that …

Systematic Metabolic Profiling Identifies De Novo Sphingolipid Synthesis as Hypha Associated and Essential for Candida albicans Filamentation

E Garbe, F Gerwien, D Driesch, T Müller, B Böttcher… - Msystems, 2022 - Am Soc Microbiol
The yeast-to-hypha transition is a key virulence attribute of the opportunistic human fungal
pathogen Candida albicans, since it is closely tied to infection-associated processes such as …