Recent studies have demonstrated that brain meningeal lymphatic vessels (MLVs) act as a
drainage path directly into the cervical lymph nodes (CLNs) for macromolecules contained …

The environment of the central nervous system (CNS) represents a double-edged sword in
the context of viral infections. On the one hand, the infectious route for viral pathogens is …

Reports regarding brain inflammation, known as encephalitis, have shown an increasing
frequency during the past years. Encephalitis is a relevant concern to public health due to its …

The persistence and clinical consequences of rabies virus (RABV) infection have prompted
global efforts to develop a safe and effective vaccines against rabies. mRNA vaccines …

Infection with laboratory-attenuated rabies virus (RABV), but not wild-type (wt) RABV, can
enhance the permeability of the blood-brain barrier (BBB), which is considered a key …

Rabies virus (RABV) infection can initiate the host immune defence response and induce an
antiviral state characterized by the expression of interferon (IFN)-stimulated genes (ISGs) …

Rabies virus (RABV) induces acute, fatal encephalitis in mammals including humans. The
circRNAs are important in virus infection process, but whether circRNAs regulated RABV …

A diverse number of DNA and RNA viruses have the potential to invade the central nervous
system (CNS), causing inflammation and injury to cells that have a limited capacity for repair …

Lyssavirus is a kind of neurotropic pathogen that needs to evade peripheral host immunity to
enter the central nervous system to accomplish infection. NLRP3 inflammasome activation is …

Rabies, caused by lyssavirus rabies (Rabies lyssavirus, RABV), is a fatal disease among
humans and almost all warm-blooded animals. In this study, we found that RABV infection …