[HTML][HTML] An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Ferroptosis and its potential role in the physiopathology of Parkinson's Disease

L Mahoney-Sánchez, H Bouchaoui, S Ayton… - Progress in …, 2021 - Elsevier
Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …

Medicinal prospects of antioxidants: A review

K Neha, MR Haider, A Pathak, MS Yar - European journal of medicinal …, 2019 - Elsevier
Free radicals generated due to exposure of radiation, environmental pollutants and as by-
products of metabolised drugs. These free radicals are antagonized by molecules which are …

Ageing, age-related diseases and oxidative stress: What to do next?

J Luo, K Mills, S le Cessie, R Noordam… - Ageing research …, 2020 - Elsevier
Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …

[HTML][HTML] Thinking outside the nucleus: Mitochondrial DNA copy number in health and disease

CA Castellani, RJ Longchamps, J Sun, E Guallar… - Mitochondrion, 2020 - Elsevier
Mitochondrial DNA copy number (mtDNA-CN) is a biomarker of mitochondrial function and
levels of mtDNA-CN have been reproducibly associated with overall mortality and a number …

[HTML][HTML] The anti-inflammatory and anti-oxidant mechanisms of the Keap1/Nrf2/ARE signaling pathway in chronic diseases

W Tu, H Wang, S Li, Q Liu, H Sha - Aging and disease, 2019 - ncbi.nlm.nih.gov
Oxidative stress is defined as an imbalance between production of free radicals and reactive
metabolites or [reactive oxygen species (ROS)] and their elimination by through protective …

[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinan-Ferre, A Bellver-Sanchis, V Izquierdo… - Ageing research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection

S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …

Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling

Y Wu, M Chen, J Jiang - Mitochondrion, 2019 - Elsevier
Mitochondrial dysfunction is becoming one of the most emerging pathological process in the
etiology of neurological disorders. Other common etiologies of the neurological disorders …

[HTML][HTML] Nanotechnology: a promising approach for delivery of neuroprotective drugs

S Naqvi, A Panghal, SJS Flora - Frontiers in Neuroscience, 2020 - frontiersin.org
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …