Role of sulphur-heterocycles in medicinal chemistry: An update
From many decades, S-heterocycles have maintained their status as an important part and
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
core of FDA approved drugs and medicinally active compounds. With exhaustive exploration …
The bioactivity of thiazolidin-4-ones: A short review of the most recent studies
D Mech, A Kurowska, N Trotsko - International Journal of Molecular …, 2021 - mdpi.com
Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …
Thiazolidin-4-one-based derivatives–Efficient tools for designing antiprotozoal agents. A review of the last decade
H Tuszewska, J Szczepański, S Mandziuk… - Bioorganic Chemistry, 2023 - Elsevier
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …
[HTML][HTML] The influence of HSP inducers on salinity stress in sterlet sturgeon (Acipenser ruthenus): In vitro study on HSP expression, immune responses, and …
Heat shock proteins (HSPs) play a crucial role in antioxidant systems, immune responses,
and enzyme activation during stress conditions. Salinity changes can cause stress and …
and enzyme activation during stress conditions. Salinity changes can cause stress and …
The anti-inflammatory activity of 2-iminothiazolidines: evidence for macrophage repolarization
ETB Mohr, TL Lubschinski, JS da Rosa, GN Vieira… - …, 2022 - Springer
Nowadays, macrophages are recognized as key cells involved in chronic inflammatory
conditions, and play central roles in all inflammatory diseases and cancer. Due to their …
conditions, and play central roles in all inflammatory diseases and cancer. Due to their …
New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile
Background Aryl-propionic acid derivatives with ibuprofen as representative drug are very
important for therapy, being recommended especially for anti-inflammatory and analgesic …
important for therapy, being recommended especially for anti-inflammatory and analgesic …
Synthesis, crystal structure, computational investigation, molecular docking analysis and anti-lung cancer activity of novel (Z)-3-amino-2-(cyclohexylidenehydrazono) …
F Ghous, S Shukla, R Singh, S Parveen… - Journal of Molecular …, 2023 - Elsevier
Ever since the disease of cancer was discovered, man has been mystified by both its
mysterious origin and the even more mystifying mechanisms by which it spreads. Although …
mysterious origin and the even more mystifying mechanisms by which it spreads. Although …
4-Thiazolidinones: A structural motif of great synthetic and biological activities
MH Younis, ER Mohammed, HH Georgey - ERU Research …, 2023 - journals.ekb.eg
Thiazolidinone heterocyclic based compounds have been extensively explored for their
potent pharmacological activities. Among several existed isomers of thiazolidinone …
potent pharmacological activities. Among several existed isomers of thiazolidinone …
A network pharmacology strategy combined with in vitro experiments to investigate the potential anti‐inflammatory mechanism of Prunus cerasifera Ehrhart
X Duan, J Li, J Cui, H Wen, X Xin… - Journal of Food …, 2022 - Wiley Online Library
This study aimed to investigate the anti‐inflammatory activity of Prunus cerasifera Ehrhart
(EHP). LC–MS/MS, network pharmacology, enzyme‐linked immunosorbent assay (ELISA) …
(EHP). LC–MS/MS, network pharmacology, enzyme‐linked immunosorbent assay (ELISA) …
Effects of HSP inducers on the gene expression of Heat Shock Proteins (HSPs) in cells extracted from sterlet sturgeon under temperature stress with antioxidant and …
Global warming has profound effects on the living conditions and metabolism of organisms,
including fish. The metabolic rate of fish increases as the temperature increases within its …
including fish. The metabolic rate of fish increases as the temperature increases within its …