Sex Differences in Mouse Models of Voluntary Alcohol Drinking and Abstinence-Induced Negative Emotion
AL Salazar, SW Centanni - Alcohol, 2024 - Elsevier
Abstract Alcohol Use Disorder (AUD) is a growing problem worldwide, causing an incredible
burden on health and the economy. Though AUD impacts people of all backgrounds and …
burden on health and the economy. Though AUD impacts people of all backgrounds and …
Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption
Y Fu, B Mackowiak, YH Lin, L Maccioni, T Lehner… - Nature …, 2024 - nature.com
Alcohol use disorder (AUD) affects millions of people worldwide, causing extensive
morbidity and mortality with limited pharmacological treatments. The liver is considered as …
morbidity and mortality with limited pharmacological treatments. The liver is considered as …
Non-consummatory behavior signals predict aversion-resistant alcohol drinking in head-fixed mice
NM Timme, CE Ardinger, SDC Weir… - …, 2024 - Elsevier
A key facet of alcohol use disorder is continuing to drink alcohol despite negative
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …
[HTML][HTML] Operant ethanol self-administration behaviors do not predict sex differences in continuous access home cage drinking
HJ Yoon, MA Doyle, ME Altemus, R Bethi, SH Lago… - Alcohol, 2024 - Elsevier
Understanding sex differences in disease prevalence is critical to public health, particularly
in the context of alcohol use disorder (AUD). The goal of this study was to understand sex …
in the context of alcohol use disorder (AUD). The goal of this study was to understand sex …
[HTML][HTML] Understanding sex differences and the translational value of models of persistent substance use despite negative consequences
Persistent substance use despite negative consequences is a key facet of substance use
disorder. The last decade has seen the preclinical field adopt the use of punishment to …
disorder. The last decade has seen the preclinical field adopt the use of punishment to …
Translating human drug use patterns into rat models: exploring spontaneous interindividual differences via refined drug self-administration procedures
G D'Ottavio, S Pezza, J Modoni, I Reverte, C Marchetti… - bioRxiv, 2024 - biorxiv.org
Heroin and cocaine users tailor their dosage and frequency of use, as well as their method
of administration, to maximize the drugs' pleasurable effects and prevent withdrawal …
of administration, to maximize the drugs' pleasurable effects and prevent withdrawal …
Medial prefrontal dopamine dynamics reflect allocation of selective attention
PR Melugin, SO Nolan, E Kandov, CF Ferrara… - bioRxiv, 2024 - biorxiv.org
The mesocortical dopamine system is comprised of midbrain dopamine neurons that
predominantly innervate the medial prefrontal cortex (mPFC) and exert a powerful …
predominantly innervate the medial prefrontal cortex (mPFC) and exert a powerful …