Mycobacterium tuberculosis infection of host cells in space and time
C Bussi, MG Gutierrez - FEMS microbiology reviews, 2019 - academic.oup.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection
Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
[HTML][HTML] Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in …
Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that exploits moonlighting
functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host …
functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host …
PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction
To the PE_PGRS protein subfamily belongs a group of surface-exposed mycobacterial
antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than 65 genes …
antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than 65 genes …
[HTML][HTML] Tuberculosis and autoimmunity
IV Belyaeva, AN Kosova, AG Vasiliev - Pathophysiology, 2022 - mdpi.com
Tuberculosis remains a common and dangerous chronic bacterial infection worldwide. It is
long-established that pathogenesis of many autoimmune diseases is mainly promoted by …
long-established that pathogenesis of many autoimmune diseases is mainly promoted by …
[HTML][HTML] Role of C-terminal domain of Mycobacterium tuberculosis PE6 (Rv0335c) protein in host mitochondrial stress and macrophage apoptosis
PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
PE_PGRS45 (Rv2615c) protein of Mycobacterium tuberculosis perturbs mitochondria of macrophages
The PE_PGRS proteins have coevolved with the antigenic ESX‐V secretory system and are
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …
[HTML][HTML] Role of the PE/PPE family in host–pathogen interactions and prospects for anti-tuberculosis vaccine and diagnostic tool design
J Qian, R Chen, H Wang, X Zhang - Frontiers in cellular and infection …, 2020 - frontiersin.org
The pe/ppe genes are found in pathogenic, slow-growing Mycobacterium tuberculosis and
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
[HTML][HTML] Virulence Factors of Mycobacterium tuberculosis as Modulators of Cell Death Mechanisms
LA Ramon-Luing, Y Palacios, A Ruiz… - Pathogens, 2023 - mdpi.com
Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host
immune responses and favor its dissemination, a complex process of interest in …
immune responses and favor its dissemination, a complex process of interest in …
[HTML][HTML] Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages
J Qian, Y Hu, X Zhang, M Chi, S Xu, H Wang, X Zhang - Microorganisms, 2022 - mdpi.com
The PE/PPE protein family commonly exists in pathogenic species, such as Mycobacterium
tuberculosis, suggesting a role in virulence and its maintenance. However, the exact role of …
tuberculosis, suggesting a role in virulence and its maintenance. However, the exact role of …