Adverse effects of antiepileptic drugs

P Perucca, FG Gilliam - The lancet neurology, 2012 - thelancet.com
More than 150 years after bromide was introduced as the first antiepileptic drug, adverse
effects remain a leading cause of treatment failure and a major determinant of impaired …

A systematic review of psychiatric and psychosocial comorbidities of genetic generalised epilepsies (GGE)

A Loughman, NA Bendrups, WJ D'Souza - Neuropsychology review, 2016 - Springer
Psychiatric disorders and associated poor psychosocial outcomes are recognised to be a
common sequelae of epilepsy. The extent to which this is true of genetic generalised …

[HTML][HTML] Depression and quality of life in patients with epilepsy in Northwest Greece

E Siarava, T Hyphantis, AH Katsanos, SH Pelidou… - Seizure, 2019 - Elsevier
Purpose The purpose of the present study was to compare depression and QoL between
patients with epilepsy and healthy controls, evaluating potentially related factors to …

Specific adverse effects of antiepileptic drugs—A true-to-life monotherapy study

AB Kowski, F Weissinger, V Gaus, P Fidzinski… - Epilepsy & Behavior, 2016 - Elsevier
Background In patients taking antiepileptic drugs (AEDs) for epilepsy, adverse effects (AEs)
often lead to unfavorable quality of life, impaired adherence, and, eventually, discontinuation …

Evaluating quality of life in epilepsy: the role of screening for adverse drug effects, depression, and anxiety

JA Micoulaud-Franchi, F Bartolomei, R Duncan… - Epilepsy & Behavior, 2017 - Elsevier
Objective The objective of this study was to evaluate the contribution of validated screening
tools for antiepileptic drug (AED) adverse effects, depression, and anxiety to measure the …

[HTML][HTML] Severity of anxiety and depression are related to a higher perception of adverse effects of antiepileptic drugs

B Gómez-Arias, D Crail-Meléndez, R López-Zapata… - Seizure, 2012 - Elsevier
After reviewing the negative effects of antiepileptic drugs (AEDs) on general health and
quality of life, the Commission on Outcome Measurement from the International League …

Medication adherence and adverse effect profile of antiepileptic drugs in Nigerian patients with epilepsy

JO Fadare, TA Sunmonu, IA Bankole… - Neurodegenerative …, 2018 - Taylor & Francis
Aim: Medication adherence remains a major challenge among patients with epilepsy (PWE)
with the adverse effect profile of antiepileptic drugs (AEDs) as one of its main drivers …

Antiepileptic drugs in migraine and epilepsy: Who is at increased risk of adverse events?

M Romoli, C Costa, S Siliquini, I Corbelli… - …, 2018 - journals.sagepub.com
Background The impact of adverse events (AEs) of antiepileptic drugs (AEDs) have an
impact on compliance and dropouts. We compared tolerability of AEs of AEDs among …

Sex Differences in Adverse Effects of Antiseizure Medications in Adults with Epilepsy: A Systematic Review

L Giuliano, V Durante, G Battaglia, S Gasparini… - CNS drugs, 2024 - Springer
Background Sex differences in epilepsy have been described in prevalence, seizure
propensity and response to treatment. Therefore, taking into account sex-based differences …

Impact of depression and anxiety on adverse event profiles in Korean people with epilepsy

SK Kim, SP Park, OY Kwon - Epilepsy & Behavior, 2015 - Elsevier
Previous studies have shown that depression and anxiety worsen the adverse events
associated with antiepileptic drugs (AEDs) in people with epilepsy. These studies used the …