Postoperative atrial fibrillation (POAF) complicates 20–40% of cardiac surgical procedures
and 10–20% of non-cardiac thoracic operations. Typical features include onset at 2–4 days …

Atrial fibrillation (AF) is associated with structural, electrical, and contractile remodeling of
the atria. Development and progression of atrial fibrosis is the hallmark of structural …

Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Rhythmic and effective cardiac contraction depends on appropriately timed generation and
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …

BACKGROUND: Atrial fibrillation (AF) is associated with increased inward-rectifier current
activity that may stabilize atrial rotors maintaining the arrhythmia. Left atrial (LA) structures …

Abstract Connexin40 (Cx40) is a major gap-junction protein in the atrial myocardium. In the
heart, gap junctions are responsible for cell-to-cell conduction of the action potential. In …

Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major
burden, both to patients and to health-care systems. In recent years, increasing evidence …

Atrial fibrillation (AF) is an extremely common arrhyth-mia with important consequences and
presently suboptimal therapeutic options. 1 A great deal of research has been performed to …

Normal atrial conduction requires similar abundances and homogeneous/overlapping
distributions of two connexins (Cx40 and Cx43). The remodeling of myocyte connections …