Multiple sclerosis is a chronic, demyelinating disease of the CNS. Cognitive impairment is a
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …

Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …

The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

Abstract See Chard and Miller (doi: 10.1093/brain/awv354) for a scientific commentary on
this article. Grey matter atrophy is common in multiple sclerosis. However, in contrast with …

The current field of multiple sclerosis (MS) research is an active and highly interesting one:
structural abnormalities such as inflammatory lesions and brain atrophy are studied with a …

Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Some of the clinical manifestations of multiple sclerosis, such as memory impairment and
depression, are, at least partly, related to involvement of the hippocampus. Pathological …

Objectives: Gray matter (GM) atrophy is common in multiple sclerosis (MS), as is cognitive
dysfunction. Understanding the exact relationship between atrophy and cognition requires …

Objective: To investigate whether extent and severity of white matter (WM) damage, as
measured with diffusion tensor imaging (DTI), can distinguish cognitively preserved (CP) …

Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …