Obesity-a risk factor for increased COVID-19 prevalence, severity and lethality

D Petrakis, D Margină… - Molecular …, 2020 - spandidos-publications.com
Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are a group of viruses that
cause infections in the human respiratory tract, which can be characterized clinically from …

Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease

D Margină, A Ungurianu, C Purdel… - Food and chemical …, 2020 - Elsevier
Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular
disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis, non …

Targeted metabolomic analysis of serum fatty acids for the prediction of autoimmune diseases

D Tsoukalas, V Fragoulakis, E Sarandi… - Frontiers in Molecular …, 2019 - frontiersin.org
Autoimmune diseases (ADs) are rapidly increasing worldwide and accumulating data
support a key role of disrupted metabolism in ADs. This study aimed to identify an improved …

Pentadecanoic acid (C15: 0), an essential fatty acid, shares clinically relevant cell-based activities with leading longevity-enhancing compounds

S Venn-Watson, NJ Schork - Nutrients, 2023 - mdpi.com
Pentadecanoic acid (C15: 0) is an essential odd-chain saturated fatty acid with broad
activities relevant to protecting cardiometabolic, immune, and liver health. C15: 0 activates …

Identification of causal metabolites related to multiple autoimmune diseases

XH Yu, RR Cao, YQ Yang, SF Lei - Human molecular genetics, 2022 - academic.oup.com
Observational studies provide evidence that metabolites may be involved in the
development of autoimmune diseases (ADs), but whether it is causal is still unknown. Based …

Sex differences in the human metabolome

M Costanzo, M Caterino, G Sotgiu, M Ruoppolo… - Biology of sex …, 2022 - Springer
Background The sexual dimorphism represents one of the triggers of the metabolic
disparities between the organisms, advising about wild implications in research or …

Application of metabolomics for unveiling the therapeutic role of traditional Chinese medicine in metabolic diseases

G Wu, W Zhang, H Li - Journal of Ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Traditional medicine has been practiced for thousands of
years in China and some Asian countries. Traditional Chinese Medicine (TCM) is …

Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins

R Mesnage, RCE Bowyer, S El Balkhi… - Environmental …, 2022 - Springer
Background Dietary habits have a profound influence on the metabolic activity of gut
microorganisms and their influence on health. Concerns have been raised as to whether the …

Metabolomic connections between schizophrenia, antipsychotic drugs and metabolic syndrome: a variety of players

JD Molina, S Avila, G Rubio… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Background: Diagnosis of schizophrenia lacks reliable medical diagnostic tests and robust
biomarkers applied to clinical practice. Schizophrenic patients undergoing treatment with …

Lipidomics: An omics discipline with a key role in nutrition

MDL de Castro, R Quiles-Zafra - Talanta, 2020 - Elsevier
The importance of lipidomics to unveil crucial aspects in the nutrition field is afforded in this
article. With this aim, historical facts such as demonization of fats, enthronization of …