Even nowadays millions of people suffer and even die each year from malaria and hundreds
of millions of people especially in tropical countries. Quinine (Q) a natural occurring alkaloid …

Malaria is one of the deadliest diseases on the planet affecting about 50% of the population
worldwide. It is a leading cause of morbidity and mortality in the developing world …

Among the most central aspects of the drug-development process is estimation of drug
levels in biological systems, which is an integral part of preclinical and clinical studies. Once …

Glassy carbon electrode was modified by electropolymerization of 4-amino-3-
hydroxynaphthalene sulfonic acid. Cyclic voltammetric study of quinine showed higher …

The capillary electrophoretic separation and immunochemical recognition of the two
naturally fluorescing, cationic diastereomers quinine (QN) and quinidine (QD), their …

Objectives Nevirapine and quinine are likely to be administered concurrently in the
treatment of patients with HIV and malaria. Both drugs are metabolised to a significant extent …

Background The varied disposition of the antimalarial quinine partly explains its poor
tolerance and toxicity in humans. Objective Using a population approach, the disposition of …

The pharmacokinetics of quinine were studied in six Nigerian patients during acute
uncomplicated falciparum malaria and convalescent periods. An oral dose of 10 mg/kg …

We investigated the effect of concurrent ingestion of Garcinia kola seed on the
pharmacokinetics of quinine. In a randomized crossover study, 24 healthy Nigerian …

Abstract Analysis of quinine in plasma and whole blood samples dried on filter paper is
described. Sample preparation involves liquid extraction of plasma and whole blood from …