The role of bacterial vaccines in the fight against antimicrobial resistance: an analysis of the preclinical and clinical development pipeline

I Frost, H Sati, P Garcia-Vello… - The Lancet …, 2023 - thelancet.com
Vaccines can be highly effective tools in combating antimicrobial resistance as they reduce
infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with …

Targeting inflammation and immunosenescence to improve vaccine responses in the elderly

B Pereira, XN Xu, AN Akbar - Frontiers in immunology, 2020 - frontiersin.org
One of the most appreciated consequences of immunosenescence is an impaired response
to vaccines with advanced age. While most studies report impaired antibody responses in …

Impact of the coronavirus disease 2019 (COVID-19) pandemic on invasive pneumococcal disease and risk of pneumococcal coinfection with severe acute respiratory …

Z Amin-Chowdhury, F Aiano, A Mensah… - Clinical infectious …, 2021 - academic.oup.com
Background Streptococcus pneumoniae coinfection with influenza results in synergistic
lethality, but there are limited data on pneumococcal coinfection with severe acute …

[HTML][HTML] Serotype replacement after introduction of 10-valent and 13-valent pneumococcal conjugate vaccines in 10 countries, Europe

G Hanquet, P Krizova, T Dalby… - Emerging infectious …, 2022 - ncbi.nlm.nih.gov
We evaluated invasive pneumococcal disease (IPD) during 8 years of infant pneumococcal
conjugate vaccine (PCV) programs using 10-valent (PCV10) and 13-valent (PCV13) …

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an …

SW Lo, RA Gladstone, AJ Van Tonder… - The Lancet Infectious …, 2019 - thelancet.com
Background Invasive pneumococcal disease remains an important health priority owing to
increasing disease incidence caused by pneumococci expressing non-vaccine serotypes …

Update on Streptococcus suis Research and Prevention in the Era of Antimicrobial Restriction: 4th International Workshop on S. suis

M Segura, V Aragon, SL Brockmeier, C Gebhart… - 2020 - mdpi.com
Streptococcus suis is a swine pathogen and a zoonotic agent afflicting people in close
contact with infected pigs or pork meat. Sporadic cases of human infections have been …

The role of vaccination in COPD: influenza, SARS-CoV-2, pneumococcus, pertussis, RSV and varicella zoster virus

S Simon, O Joean, T Welte… - European Respiratory …, 2023 - Eur Respiratory Soc
Exacerbations of COPD are associated with worsening of the airflow obstruction,
hospitalisation, reduced quality of life, disease progression and death. At least 70% of …

Acute bacterial meningitis

EC Wall, JM Chan, E Gil… - Current opinion in …, 2021 - journals.lww.com
Acute bacterial meningitis : Current Opinion in Neurology Acute bacterial meningitis :
Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get new …

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact

RA Gladstone, SW Lo, JA Lees, NJ Croucher… - …, 2019 - thelancet.com
Background Pneumococcal conjugate vaccines have reduced the incidence of invasive
pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a …

Emerging vaccine strategies against the incessant pneumococcal disease

JA Duke, FY Avci - npj Vaccines, 2023 - nature.com
The incidence of invasive pneumococcal disease (IPD) caused by infection with the
pathogen Streptococcus pneumoniae (Spn) has been on a downward trend for decades due …