Background New drugs and new evidence concerning the use of established treatments
have become available since the publication of the first European League Against …

Asymptomatic MSU crystals deposits can now be identified and precede the onset of gout
flares. Defining hyperuricemia as greater than 6 mg/dl would have the advantage to give the …

Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia …

Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory
arthritis. By combining data from> 140,000 individuals of European ancestry within the …

Context Patients with chronic disabling gout refractory to conventional urate-lowering
therapy need timely treatment to control disease manifestations related to tissue urate crystal …

Objective To develop response criteria for adult dermatomyositis (DM) and polymyositis
(PM). Methods Expert surveys, logistic regression, and conjoint analysis were used to …

Introduction The purpose of this study was to compare urate-lowering (UL) efficacy and
safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA)≥ 8.0 …

The aim of this review is to provide a summary of adult measures of general health and
health-related quality of life (HRQOL) commonly used in rheumatology research studies …

We aimed to develop evidence-based multinational recommendations for the diagnosis and
management of gout. Using a formal voting process, a panel of 78 international …

Objective Gout is the most common cause of inflammatory arthritis in men, but has not
previously been included in Global Burden of Disease (GBD) studies. As part of the GBD …