Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disease.
HCM is a highly complex and heterogeneous disease regarding not only the number of …

During the past two decades, numerous disease-causing genes for different
cardiomyopathies have been identified. These discoveries have led to better understanding …

The Angiotensin system is implicated in the pathogenesis of COVID-19. First, ACE2 is the
cellular receptor for SARS-CoV-2, and expression of the ACE2 gene could regulate the …

Background Two mutations in the MYBPC 3 gene have been identified in M aine C oon
(MCO) and R agdoll (RD) cats with hypertrophic cardiomyopathy (HCM). Objective This …

Background: Genetic factors in the pathogenesis of cardiomyopathies have received a lot of
attention during the past 2 decades. Some studies have reported that angiotensin …

Aim: The long noncoding RNA H19 and its host micro RNA miR-675 have been found
deregulated in cardiac hypertrophy and heart failure tissues. Our aim was to investigate …

Due to the inconsistent findings from various studies, the role of gene polymorphisms in the
renin-angiotensin system in influencing the development of cardiomyopathy remains …

肥厚型心肌病(Hypertrophic cardiomyopathy, HCM) 是以左心室及室间隔不对称肥厚为基本
特征的原发性心肌病, 其发病率约为0.2%, 是青少年和运动员心源性猝死的最常见原因. HCM …

Large panels of studies have examined the association between angiotensin-converting
enzyme (ACE) gene insertion/deletion (I/D) polymorphism and risk for left ventricular …

There is no agreement on the involvement of angiotensin II type 1 receptor (AT1R) gene
A1166C variant and essential hypertension. The purpose of this study was to investigate the …