The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

The chemistry of nitrogen-centered radicals (NCRs) has plentiful applications in organic
synthesis, and they continue to expand as our understanding of these reactive species …

The concept of strain in organic compounds is as old as modern organic chemistry and was
initially introduced to justify the synthetic setbacks along the synthesis of small ring systems …

Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward
approach to the efficient synthesis of functionalized complex molecules. However, C–H LSF …

Electrochemistry has emerged as a powerful means to enable redox transformations in
modern chemical synthesis. This tutorial review delves into the unique advantages of …

Bimolecular homolytic substitution (SH2) is an open-shell mechanism that is implicated
across a host of biochemical alkylation pathways. Surprisingly, however, this radical …

Carboxylation of easily available alkenes with CO2 is highly important to afford value‐added
carboxylic acids. Although dicarboxylation of activated alkenes, especially 1, 3‐dienes, has …

Radical reactivity is a powerful tool for molecular construction that often provides bond-
forming strategies and retrosynthetic disconnections complementary to those available …

Site-and enantioselective cross-coupling of saturated N-heterocycles and carboxylic acids—
two of the most abundant and versatile functionalities—to form pharmaceutically relevant α …

A visible light-induced palladium-catalyzed homologative three-component synthesis of
allylic amines has been developed. This protocol proceeds via a unique mechanism …