Mechanobiology research is for understanding the role of mechanics in cell physiology and
pathology. It will have implications for studying bone physiology and pathology and to guide …

The coupled hydrology and mechanics of soft porous materials (such as clays, hydrogels,
membranes, and biofilms) is an important research area in several fields, including water …

Recent evidence suggests that mechanical deformation of the cell nucleus regulates the
nuclear import of the transcriptional activators of genes involved in primary physiological cell …

We present an immersed finite element technique for boundary-value and interface
problems from nonlinear solid mechanics. Its key features are the implicit representation of …

Perfusion bioreactors regulate flow conditions in order to provide cells with oxygen, nutrients
and flow-associated mechanical stimuli. Locally, these flow conditions can vary depending …

A numerical procedure that combines an extended finite element formulation and a
discontinuous Galerkin technique is presented, with the final aim of providing an effective …

Despite the relevant regulatory role that nuclear deformation plays in cell behaviour, a
thorough understanding of how fluid flow modulates the deformation of the cell nucleus in …

In this work, we bridge standard Adaptive Mesh Refinement and coarsening (AMR) on
scalable octree background meshes and robust unfitted Finite Element (FE) formulations for …

Epithelial tissues show a particular topology where cells resemble a polygon‐like shape, but
some biological processes can alter this tissue topology. During cell proliferation, mitotic cell …

The automated finite element analysis of complex CAD models using boundary-fitted
meshes is rife with difficulties. Immersed finite element methods are intrinsically more robust …